Dosage form:intravenous solution (15 mg/mL), oral solution (5 mg/mL), oral tablet (120 mg; 160 mg; 240 mg; 80 mg; AF 120 mg; AF 160 mg; AF 80 mg) Drug classes:Group III antiarrhythmics,Non-cardioselective beta blockers
For a child aged about 1 week, the initial starting dose should be multiplied by 0.3; the starting dose would be (30 X 0.3) = 9 mg/m2. Similar calculations should be made for increased doses as titration proceeds. Since the half-life of Sotalol decreases with decreasing age (below ...
The groups had similar demographics. Group 1 included patients with atrial flutter (n = 16), patients with supraventricular tachycardia (SVT) (n = 9), and patients with atrial ectopic tachycardia (AET) (1). All 9 patients with SVT (100%) converted to sinus rhythm after failure to convert...
The average length of hospital stay was similar in the two groups (6.8 days vs 7.4 days, P = 0.558). CONCLUSION: Initiating sotalol at 120-160 mg orally twice per day marginally increases the risk of cardiac and non-cardiac side effects compared to the standard starting regimen of 80 mg ...
We focused on the first demonstration that antiarrhythmics, particularly class II and class III antiarrhythmic and beta-blocker sotalol can induce severe occlusion/occlusion-like syndrome in rats. In this syndrome, as in similar syndromes with permanent