Whole red cells, red cell membranes or soluble blood group substances prepared from individuals with blood group A1, A2, B or A2B were used as immunogens. A large number of mouse-mouse hybridomas with anti-A, anti-B and anti-A, B specificity was produced. Several of these antibodies ...
Searching databases for monogenic diseases that display Mendelian inheritance revealed over 50 genes, which primarily encode adhesome signalling proteins, that are involved in human diseases (predominately cancer). An additional set of 138 adhesome genes was shown to be genetically associated with diseas...
Sperm antibodies and their action upon human spermatozoa are discussed. Some infertile men possess autoantibodies against spermatozoa in seminal plasma and blood stream. These autoantibodies agglutinate and sometimes immobilize spermatoz... O'Bryan M.K,Liu D.Y,Morrison J.R,... - 《Human Reproducti...
The results indicate presence of G proteins coupled P2Y receptors on ependymocytes and also P2X receptors engaged in fast signal transmission. Additionally we found in CSF nucleotides and adenosine in the concentration sufficient to P receptors activation. These extracellular nucleotides are metabolised...
Although conventional imprinting involving the use of charged functional monomers has been used by many authors for selective adsorption of small molecules, it has not been very successful with high-molecular-weight substances, for example proteins (“...macromolecules, such as proteins are difficult ...
Although these steps are described as separate processes, there is ample of evidence that they are not completely separate and that the same proteins participate in or contribute to multiple steps, suggesting these steps’ continuity. Nevertheless, in the following section, each of these steps is ...
Researchers hope these antibodies will someday form the basis of a simple blood test to screen for MS. "Over the last few decades, there's been a move in the field to treat MS earlier and more aggressively with newer, more potent therapies," said senior researcher Dr. Michael Wilson, a...
However, it is not clear what proteins are functionally involved in this process. Here we show that a novel chromatin activity-based chemoproteomic (ChaC) approach can dissect the functional chromatin protein complexes that regulate ET-associated inflammation. Using UNC0638 that binds the enzymatically...
(magnetotaxis) proteins. Most of these proteins are encoded by several operons within a genomic magnetosome island (MAI) of 100–130kb, which is conserved between several MTB, and which may have been acquired by horizontal gene transfer. Cloning and transfer of all of the about 30 relevant ...
The predicted masses of these blood-stage alveolins are 62, 34, and 30 kDa, respectively, so the proteins migrate more slowly than expected, which has been reported previously for the alveolins of other species (34). Interestingly, the solubility of the blood-stage alveolins was similar to ...