experiment and (2) the large native effector YopO and its chaperone SycO. In bacteria with a functional T3SS, the plasmid used for the expression of YopO and SycO allowed for the secretion of YopO, indicating that YopO and SycO are expressed and functionally interact (Supplementary Fig.3). We...
Eukaryotic enhancers are classically depicted as clusters of transcription factorbinding sites(TFBS), found somewhere in the genomic neighborhood of the gene(s) they regulate, where they integrate signals from the cellular environment to direct the timing, levels, and cell-type specificity of gene exp...
OPLS-DA model (Fig.4A) prescribed by four components effectively discriminated the four algae species into two main clusters along two orthogonal PCs, justifying 75% of the entire variance within samples. The performance of the constructed model was validated by the computed parameters “R2(0.998)...
elongatus was solved at a resolution of 2.5 Å (Fromme et al., 2001; Jordan et al., 2001); a PSI monomer was shown to contain 12 protein subunits (PsaA-F, PsaI-M, and PsaX) and 127 cofactors: 96 Chls and 22 Cars; 2 phylloquinones (A1A and A1B); 3 [4Fe-4S] clusters;...
I found a bag of Christmas bits and pieces in a cupboard when I was looking for something else and knew I could incorporate them on a very plain wreath I already had but hadn’t used in the past. The wreath had clusters of red berries and little lights run off batteries and could ...
(139 genes). In addition, the results of Clusters of Orthologous Groups (COG) annotations showed that the genome of CS2105-BJ has a complete set of genes required for the de novo synthesis of vitamin B12(called B12hereafter), also known as cyanocobalamin (Fig.3b). It is well known that...
In eukaryotic organisms, gene expression is regulated at multiple levels during the processes of transcription and translation. The absence of a tight regulatory network for transcription in the human malaria parasite suggests that gene expression may la
(CLSM) analysis, while untreated HOFs did not form degradative cortactin clusters, under the addition of ET-1, F-actin/cortactin puncta became visible within the cell body, displaying invadosome properties, as degradative activity, but not when cells were treated with AMB or BQ788, or BOS (...
Lanes are marked as for the sucrose gradient fractions in Fig. 1A. C: Peptides of interest (bands 1–12 excised from 2A) identified using a MALDI-TOF mass spectrophotometer. Peptides marked in red font represent variants with the same function, but encoded by different genes. ApcA and A...
clusters of lysine residues located opposite to each other on the surface of the globular domain. One cluster binds to the nucleosomal DNA near the dyad, and the other interacts with 10 bp of one linker DNA. Two discrete lysine-rich short regions of the CTD are also involved in this ...