基因别名 : CD25, IDDM10, IL2R, IL2RA, IMD41, p55, TCGFR 基因ID : (Human) 3559 基因符号 : IL2RA 蛋白别名 : CD25, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA,...
P 133 Soluble IL2 receptor, sCD4, sCD8 and IFN-γ in active BD patients with pulmonary manifestationsInterleukin-6, a potent pro-inflammatory cytokine, might be involved in Behet's disease (BD) pathological pathways. We investigated IL-6 levels in sera and synovial fluids collected from BD ...
Simplified representation of signal transduction via the T-cell receptor – CD3 complex eventually results in expression of multiple genes, including the IL2 gene (A). This requires the combined action of three transcription factors, being NF-AT, NF-κB and AP-1. Activation of NF-AT can be ...
Serum from 77 children with JIA and 81 pediatric controls was analyzed for interleukin (IL)1β, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL13, sCD154, interferon-γ (IFNγ), soluble IL2 receptor (sIL2R), and tumor necrosis factor-α (TNFα), using the Luminex Multi-Analyte Profil...
in parallel with ERα studies in hormone receptor-negative breast cancer therapy, ligand-mediated activation of ERβ has also shown potent anti-proliferative effects in TNBC cells through the suppression of metastatic phenotypes22,23,24. It is possible that RNF208 expression may be associated with...
SOLUBLE IL2 RECEPTOR AND SURVIVAL IN RECENT ONSET CARDIOMYOPATHY: RESULTS OF IMAC2Background-Black women are at greater risk for peripartum cardiomyopathy (PPCM). The guanine nucleotide-binding proteins 尾-3 subunit (GNB3) has a polymorphism C825T. The GNB3 TT genotype more prevalent in blacks...
Intriguingly, hepatic levels of Ccl2, Adgre1, Il2, and Acta2 mRNAs were reduced, and Tnfa trended lower in HFHC-fed Dpp4Hep−/− mice (Figures 4A and S5A). Levels of the M2 anti-inflammatory macrophage markers Mgl2 and Arg1 were unchanged (Figure S5A), and the mRNA encoding the...
Kuehbacher T, Nikolaus S, Schreiber S. Serum soluble IL2-receptor is increased in a subpopulation of Crohns disease patients, who respond to open label use of ustekinumab, a human monoclonal antibody to IL-12/23p40 (abstract). Gastroenterology. 2011;140(5):S-589....
Alterations of gamma aminobutyric acid (GABA) neuronal function and benzodiazepine receptor (BZR) function in particular have been implicated in the pathophysiology of severe, chronic tinnitus. The purpose of our study was to evaluate the distribution of BZR in the brain using 123I-iomazenil single...
Peripheral Blood TCRβ Repertoire, IL15, IL2 and Soluble Ligands for NKG2D Activating Receptor Predict Efficacy of Immune Checkpoint Inhibitors in Lung CancerSPAINMORTALITY risk factorsRISK assessmentT cellsRESEARCH fundingSCIENTIFIC observationTUMOR markers...