5, 1968 United States Patent wthee TMPROVING SOLUBILITY OF HIGH-MOLECU- LAR WEIGHT SUBSTANCES. BY. DIALDEHY DE POLYSACCHARIDE TREATMENT Franz Schwarzer, Wiesbaden, and Hans Macholdt,Wiesbaden-Biebrich, Germany, 'assignors to Kalle Aktiengesellsclraft, Wiesbaden-Bicbrich, Germany, a corporation of...
This work is a continuation of our systematic study of the solubility of pharmaceuticals (Pharms). All substances here are derivatives of anthranilic acid, and have an anti-inflammatory direction of action (niflumic acid, flufenamic acid, and diclofenac sodium). The basic thermal properties of pur...
Furthermore, the aqueous complexation of three organic ligands to Al3+ was examined as a function of ionic strength, to enable a quantitative modeling of ligand promoted gibbsite solubilization, and other phenomena discussed in this context is the appearance of crystallization inhibiting substances and...
There are relatively more molecules with clogP > 5 in the new drugs set (15% of NMEs), compared to that of the training set (6%). For the new drugs, 28% of the substances have MW > 500 g·mol–1, compared to 7% in the training set. The relative number of NHD >...
Solubility gives the extent to which a solute can be dissolved in a solvent. When a solute is mixed with solvent, intermolecular forces of solute particles becomes less effective and solute ionizes i.e. breaks down into constituent ions which interact with solvent and form ...
solid high-molecular-weight organic substancessupercritical fluidsorganic supercritical fluidsA method is proposed to calculate the solubility of solid high-molecular-weight substances in organic supercritical fluids on the basis of the Soave and Peng–Robinson equations of state. The mixing rules are ...
Discussing the further development of the sequence design scheme based on PAT involving macromolecular substances modified by a low-molecular-weight reactant, it is of interest to consider how differences in the solubility of a homopolymer and modified monomeric units affect the sequence of the resulti...
Bile salts and phospholipids in the gastrointestinal tract can improve the wettingCitation31 and solubilityCitation32,Citation33 of many lipophilic substances. Additionally, interactions between intestinal fluids, lipids, and food can enhance the formation of emulsions.Citation34 In vitro, various synthetic...
An excess of alkali carbonate also inhibits its action. Pancrelipase: Cream-colored, amorphous powder, having a faint, characteristic, but not offensive odor. Pancrelipase hydrolyzes fats to glycerol and fatty acids, changes protein into proteoses and derived substances, and converts starch into ...
Investigation of overfoaming activities and gushing mechanisms of individual beer ingredients as model substances in bottled carbonated water model beer ingredients.RESULTSGushing formation of the investigated beer ingredients depends on the degree of stabilized solvated molecular carbon dioxide in ... AA Ay...