1 Henry’s Law Coefficient (Solubility) of Toluene in Water with GC-FID A laboratory experiment for junior level undergraduate Analytical Chem..
The solubility of water in 1-hexanol, 1-octanol, 1-decanol, and cyclohexanol was determined as a function of water activity by the isopiestic method at 298.2K. The solubility of water in the alcohol was expressed by a Setchenov type of equation and the correlation coefficients were related ...
Hydrophobicity of the drug molecule, indicated by the octanol–water partition coefficient, influences solvation of a drug in water. Higher the hydrophobicity, poor the water-drug interaction, lower the solvation, and, consequently, lower the aqueous solubility of the drug. Crystal lattice energy is...
Part 2. Solubility in 1-octanol. SAR and QSAR Environ. Res. 18 (5-6), 543-578.Raevsky OA, Grigor'ev VJ, Raevskaja OE, et al . Physicochemical properties/descriptors governing the solubility and partitioning of chemicals in water-solvent-gas systems. Part 1. Partitioning between octanol ...
Martínez, F., Gómez, A.: Thermodynamic study of the solubility of some sulfonamides in octanol, water, and the mutually saturated solvents. J. Solution Chem.30, 909–923 (2001) ArticleGoogle Scholar Yeo, S.-D., Lee, JCh.: Crystallization of sulfamethizole using the supercritical and liqu...
Correlation Analysis Between Watersolubility, Octanol-water Partition Coefficient and Melting Point Based on ClusteringJohan Nouwen, Björn Hansen First published: 1996 https://doi.org/10.1002/qsar.19960150105 Citations: 10 PDF Tools Share Abstract By means of clustering according to structure similarity...
A database (n = 50) consisting of values of solubility in water, SAQ, solubility in octanol, SOCT, molecular weight, MW, and maximum flux based on the delivery of total species containing a parent drug by its prodrugs through human skin in vitro from water has been integrated into the ...
Thermodynamic study of the solubility of some sulfonamides in octanol, water, and the mutually saturated solvents. J. Solution Chem. 2001, 30, 909-923.MARTINEZ, F.; AVILA, C.M.; GOMEZ, A. Thermodynamic study of the solubility of some sulfonamides in cyclohexane. Journal of the Brazilian ...
Would you expect sucrose (table sugar) to have greater solubility in water or in hexane? Explain. Why is the solubility of butane 6.1 mg / 100 g water, yet hexane is immiscible in water? Why is octanol soluble in both water and hexane? Are hexane and methylene chlorid...
Studies of the fate of chemicals require the knowledge of numerous parameters, among which of utmost importance are the water solubility and the n-octanol/water partition coefficient. Numerous writers have demonstrated that there is a close correlation between these two parameters. The literature offers...