It also compiles the patents, case studies of successful topical delivery with these drug carriers and their use in finished marketed products available world-wide.doi:10.1016/B978-0-12-816705-2.00001-1Indu Pal KaurGarima SharmaMandeep Singh...
This study aims to develop ezetimibe-loaded solid lipid nanoparticles (SLNs) and compare them with marketed product and drug suspension for dissolution and bioavailability. Ezetimibe-loaded SLNs were fabricated using high pressure homogeniser (HPH). The content of SLNs were (drug, solid lipid and...
The traditional intravenous administration of AmB in the current marketed formulations results in high drug levels in target organs, but is also associated with significant accumulation in the kidneys, which is highly problematic, as the drug is a known nephrotoxin. In a recent...
Polymers commonly used for enteric coating are cellulose acetate phthalate, HPMCP, HPMCAS, polymethacrylates (marketed as Eudragit®), and polyvinyl acetate phthalate (Siepmann et al., 2006, Thoma and Bechtold, 1999). The pH dissolution threshold of an enteric polymer varies with polymer chemistry...
Patents involving natural fats and oils in SLN and NLC composition are listed, yet it is important to note that the approved marketed formulations are mainly cosmetic, not pharmaceutical, products. Conclusion Natural lipids can enhance topical drug delivery by adding their ability of improving skin ...
The treatment of cancer is still a major challenge. But tremendous progress in anticancer drug discovery and development has occurred in the last few decades. However, this progress has resulted in few effective oncology products due to challenges associated with anticancer drug delivery. Oral administ...
This study aims to develop ezetimibe-loaded solid lipid nanoparticles (SLNs) and compare them with marketed product and drug suspension for dissolution and bioavailability. Ezetimibe-loaded SLNs were fabricated using high pressure homogeniser (HPH). The content of SLNs were (drug, solid lipid and...
Keywords: idebenone; solid lipid nanoparticles; nanocarriers; pyroglutamic acid; idebenone derivative; antioxidant activity; ORAC assay; anti-glycation activity; skin hydration 1. Introduction The advantages of solid lipid nanoparticles (SLN) as drug delivery systems have been widely reviewed [1–4]. ...
Nanoparticles can be functionalized to enable targeted drug delivery, binding specifically to desired cells or tissues, reducing off-target effects and systemic toxicity. Liposomes, polymeric nanoparticles, lipid nanoparticles, dendrimers, carbon nanotubes, and inorganic nanoparticles are common types used in...
Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv. Drug Deliv. Rev. 2007, 59, 478–490. [Google Scholar] [CrossRef] Jabbal-Gill, I. Nasal vaccine innovation. J. Drug Target. 2010, 18, 771–786. [Google Scholar] [CrossRef] Sharma, S.; Mukkur, T....