biopharmaceutics classification system class II drugssolid lipid nanoparticlesIn drug discovery, approximately 70% of new drug candidates have shown poor aqueous solubility in recent years. Currently, approximately 40% of the marketed immKumar, Hitesh...
size, safety, ability to encapsulate various drugs, biocompatibility, and excellent modulation, liposomal colloidal drug carriers are good alternatives as a drug transporter compared to the expensive polymers [22]. Solid lipid nanoparticles (SLNs) are member of lipid nanoparticles, which due to their ...
Nanostructured lipid carrier PEG: Polyethylene glycol PVP: Poly(vinylpyrrolidone) SLN: Solid lipid nanoparticles SR: Sustained release Tg: Glass-liquid transition temperature References Aboelwafa AA, Basalious EB (2010) Optimization and in vivo pharmacokinetic study of a novel controlled release...
Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment 2023, Advances in Colloid and Interface Science Show abstract A concise review on cancer treatment methods and delivery systems 2019, Journal of Drug Delivery Science and Technolog...
Chitosan and solid lipid nanoparticles (SLNs) have demonstrated great abilities as delivery systems in enhancing the bioavailability of therapeutic compounds. The present study aimed to get together the biological features of SLNs with the advantages of chitosan to formulate an efficient nano-carrier ...
Lipid nanoparticles LV: Lentiviral vector MDSCs: Myeloid-derived suppressor cells MHC: Major histocompatibility complex MM: Multiple myeloma NAD+ : Nicotinamide adenine dinucleotide NC: Synthetic polymer nanocarriers NHL: Non-Hodgkin’s lymphoma
Ion transport and hydrodynamic flow through nanometer-sized channels (nanopores) have been increasingly studied owing to not only the fundamental interest in the abundance of novel phenomena that has been observed but also their promising application in
In this study, a novel multi-scale drug encapsulation system, curcumin-Solid Lipid Nanoparticles (SLNs) loaded chitosan microparticles, has been formulated by combining biopolymer- and lipid-based drug delivery systems. Curcumin was loaded into phospholipids / Tween 80 stabilized shea butter SLNs (C...
there is a greater chance that T cells may use glucose, which will improve anti-tumor immunity [208]. Qin and colleagues developed an in situ nanovaccine (TPOP) that leverages nanoparticles to modulate lipid metabolism and activate the innate immune system. Combined with immune checkpoint inhibitor...
lipid-based formulations are: spray congealing/drying, adsorption on solid carriers, melt granulation/melt extrusion, supercritical fluid based methods, or processing of solid lipid nanoparticles (9). The major difference between these methods is whether or not solvents are applied during the process....