Solid dosage forms of tablets, dragees, capsules, pills, and granules can be prepared with coatings and shells such as enteric coatings and other coatings well known in the pharmaceutical formulating art. They may optionally comprise opacifying agents and can be of a composition that they release...
Preferred dosage forms of this invention minimize this degradation. FIG. 3 shows the difference between two tablets of the invention—formulations 6 and 8, described in the examples below—and a capsule dosage form that was used in human Phase 1 and 2 clinical trials. The capsules contained a...
Semi Solid DFs, Routes of Administration, ointment, paste, cream, ideal properties of a base, characteristics of ointment bases & specific examples, genera…
In order that the invention described herein may be more fully understood, the following examples are set forth. It should be understood that these examples are for illustrative purposes only and are not to be construed as limiting this invention in any manner. EXAMPLES Methods & Materials Differe...
Examples of various excipients used in solid oral dosage forms have beenincluded to elaborate on different drug-excipient interactions.KEYWORDS: drug-excipient interactions; solid dosage form; excipient stability; chemicalincompatibility; oxidative degradation.INTRODUCTIONExcipients are inactive ingredients added ...
Puerto Rico. The enhancements are expected to come on-line in late 2006. Patheon acquired the Manati site and facilities in Caguas and Carolina, Puerto Rico in 2004 with the acquisition of Mova Pharmaceutical Corporation, a contract manufacturer of solid, liquid, sterile-liquid dosage forms and ...
Slow solvent evaporation, slow cooling crystallization, and slurry conversion are examples of solution-based approaches for pharmaceutical cocrystallization. Neat grinding, ball milling, and hot melt extrusion are examples of solvent-less approaches. Recently, some hybrid methods have been developed for ...
Liquid formulations are preferred to solid dosage forms as they are easier to administer, have better bioavailability, and fewer side effects. The size of particles varies for different drugs and primarily depends on the rheological properties of the formulation and the physiochemical characterization of...
Reports on application of the technique to produce solid pellets, termed as “liquid-pellets,” have also shown promise.10The guiding principles for preparation of liquisolid tablets or pellets have been summarized in Figure 3. As indicated in the previous examples, the process requires s...
Specific aspects of semi-solid dosage forms for topical application include the nature of the barrier to be overcome, aspects of susceptibility to physical and chemical instability, and a greater influence of sensory perception. Advances in understanding the driving forces of skin penetration as well ...