Therefore, we successfully developed a new scale-down methodology to optimize the formulation of plant-derived soft gel capsules on a commercial scale.doi:10.1016/j.ijpharm.2017.11.029Oishi, SanaKimura, Shin-ichiroNoguchi, ShujiKondo, MioKondo, YosukeShimokawa, YoshiyukiIwao, YasunoriItai, ShigeruInt J Pharm
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The present invention relates to soft gelatin capsules characterized in that the shell includes a cyclodextrin and in that the filling material contains a liposoluble drug capable o
A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising