别名 [14C]-Sodium Valproate、Depakote ER、Divalproex + [13] 靶点 GABA receptor x Sodium channels 作用机制 GABA receptor激动剂(γ-氨基丁酸受体激动剂)、钠通道阻滞剂 治疗领域 神经系统疾病其他疾病 在研适应症 躁郁症偏头痛癫痫的复杂部分性发作+ [2] 非在研适应症 酒精相关疾病酗酒躁郁症1型+ [3] ...
addition of fe lbamate has been reported8 to necessitate a reduction in warfarin dosage. in another patient there was a transient increase in response to warfarin when valproic acid was started.9 valproate also inhibits platelet function and caution is required with warfarin and other anticoagulants...
In another patient there was a tran- sient increase in response to warfarin when valproic acid was started.8 Valproate also inhibits platelet function and caution is required with warfarin and other anticoagulants. For the effect of oral anticoagulants on phenytoin, see p.498. 1. Hansen JM, et...