Sodium alginate crosslinking moxifloxacin sustained-release microspheres and preparation method and application thereof, and vascular target suppository containing microsphereThe invention relates to sustained-release microspheres which are crosslinked by taking sodium alginate as a carrier and contains moxifloxacin...
Alginate has wide applications. For example, one of its most important role is being used as wound dressing materials for the treatment of acute or chronic wounds. The use of alginate crosslinking to make hydrogels for cell encapsulation is also quite valuable. The emergence of various kinds of...
Sodium alginate, CaCl2, glycerin,Utech L100 piercing-solidifying incuber method 94 % embedding rate Tight and porous structure (Yu, 2020) Chitosan,Tripolyphosphate, glutaraldehyde Series crosslinking technology More than 90 % embedding rate Particle size 198 nm (Kapoor et al., 2015) Show moreView ...
alginate. However, due to its fast reversible ionic crosslinking process, the common ion crosslinked alginate gel will dissociate in vitro, resulting in a 40% loss of its mechanical properties in 9 days (Shoichet et al., 1996). If the carboxyl group of thesodiumalginate monomer is reacted ...
140 to 350 nm and were rendered stable in water via simultaneous ionic-crosslinking SA and crystallization of PVA (5% CaCl 2 in 75% EtOH for 30 min). This aqueous electrospinning and physical crosslinking approach is a green and highly efcient alternative to create alginate hybrid bers that ...
) on the bead strength. Meanwhile, for G4 encapsulation yield, only genipin showed less significant effect on the response. However, the use of this matrix remained due to the intermolecular cross-linking ability with bovine gelatin. Optimum compositions of bovine gelatin-genipin-sodium alginate ...
The molecular structure of PAM includes numerous active functional groups, which can form a network structure through chemical crosslinking and act as the basic framework for hydrogel. Sodium alginate (SA), a biopolymer derived from brown algae [13,14], was utilized to create a physical cross...
The production of spheres loaded with acetaminophen by the cross linking technique was achieved. The hydrophilic polymer sodium alginate which gels in presence of a cross linking ion was used as a matrix for the spheres production. Two processing variables were studied. The drug load in the formul...
3c). This is mainly due to the decreased pore size of the composite films due to the increased cross-linking density. The excellent water vapor, CO2, and O2 barrier properties of the composite films can effectively reduce the water loss of the fruit, and inhibit the respiration and ...
and 36 indicates that a cross-linking occurred that was not alleviated by increasing the Na2CO3content (Examples 31 and 36) or by decreasing the Na5P3O10content (Example 36). Moreover, the low level of xanthan K9C57 in Examples 50 and 52 (0.13%) can be compared directly to Examples 35 an...