Figure 3.Potential mechanisms of Serum Uric Acid Reduction. Abbreviations: SGLT2i, Sodium–glucose cotransporter 2 inhibitors; SUA, serum uric acid; UA, uric acid; ABCG2, ATP-binding cassette subfamily G member 2. Created with BioRender.com (accessed on 6 May 2023). ...
Heart failure (HF) with mid-range or mildly reduced ejection fraction (HFmrEF) is a separate clinical entity in the HF spectrum, with a left ventricular ejection fraction ranging from 40 to 49%. While sodium glucose co-transporter 2 inhibitors have becom
Treating type 2 diabetes (T2D) patients with sodium–glucose cotransporter 2 (SGLT2) inhibitors may be associated with an increased risk of urinary tract infections (UTIs), such as diabetes-induced asymptomatic bacteriuria. Pyuria—a condition wherein leukocytes are detected in the urine—is a pred...