Social memory engram in the hippocampus. Neurosci. Res. 129, 17–23 (2018). Article PubMed Google Scholar Hitti, F. L. & Siegelbaum, S. A. The hippocampal CA2 region is essential for social memory. Nature 508, 88–92 (2014). Article ADS CAS PubMed PubMed Central Google Scholar ...
We reasoned that hippocampal engrams, which represent ensembles of neurons with increased activity after memory formation, could underlie some contributions of the hippocampus to depression symptoms. Using the chronic social defeat stress model, we examined social defeat-related h...
Acquiring and exploiting memories of rewarding experiences is critical for survival. The spatial environment in which a rewarding stimulus is encountered regulates memory retrieval. The ventral hippocampus (vH) has been implicated in contextual memories
Ramirez, S. et al. Activating positive memory engrams suppresses depression-like behaviour.Nature522, 335–339 (2015).Study showing that optogenetic dissecting of a memory engram is possible. CASPubMedPubMed CentralGoogle Scholar Namburi, P. et al. A circuit mechanism for differentiating positive ...
In Search of Engram Cells Learning and Memory: A Comprehensive Reference, 2017, pp. 637-658 Dheeraj S. Roy, Susumu Tonegawa Short day length enhances physiological resilience of the immune system against 2-deoxy-d-glucose-induced metabolic stress in a tropical seasonal breeder Funambulus pennanti ...
They identify the ventral hippocampus in the brain as critical for storing a social memory, or engram, with connectivity to the nucleus accumbens as key to the expression of such a memory (see the figure). Authors: Kapil Saxena, Richard G. M. MorrisKapil Saxena...
The hippocampus (HPC) is an extensively studied structure with a well-defined role in declarative memory, which includes memory of places, people, events, and facts1. As declarative memory consists of distinct stages, including encoding, consolidation, and recall, a key question is the extent to...
[19,20,21]. PVN OXT neurons extensively innervate to many emotion- and social-related nuclei, including the ventral tegmentum area (VTA), nucleus accumbens (NAc), amygdala, hippocampus and prefrontal cortex, etc., linking to functions such as participation in social recognition memory, mother-...
maintenance of social memory in mice35,36,37, although did not affect other hippocampus-dependent memories36. Interestingly, enriched environment blunted the effect of SI on memory36in a neurogenesis-dependent manner38. In fact, the formation of social recognition memory seems reliant on neurogenesis...