英夫利昔单抗治疗可早期非持续性改善顽固性角层下脓疱病(Sneddon-Wilkinson病):与吸疱液内细胞因子变化的关系 角层下脓疱病单抗治疗细胞因子变化持续性依曲替酯光化疗法氨苯砜阿维糖皮质激素Subcorneal pustular dermatosis (SCPD) is an uncommon disorder, characterized by a chronic relapsing vesiculopustular ...
英文: Skin biopsy findings indicated a drug-induced pustular dermatitis.中文: 皮肤病理所见表明是药物引起的脓疱性皮炎。英文: Histological examination showed pustular dermatitis with spongiform pustules, consistent with a drug eruption.中文: 组织学检查显示为海绵状脓疱性皮炎,符合药疹的改变。
Subcorneal pustular dermatosis (SCPD, Sneddon-Wilkinson disease) is a rare chronic-relapsing skin disorder that typically manifests as flaccid sterile pustules without systemic symptoms. Although the accumulation of neutrophils is acknowledged to be a hallmark of SCPD, its exact pathomechanism is still...
These reports led to major changes in routine prescriptions in dermatology, making this molecule a first option for many skin inflammatory disorders such as acne and rosasea. To the best of our knowledge, doxycycline has never been used in the treatment of Sneddon Wilkinson disease or Subcorneal...
Subcorneal pustular dermatosis (SPD) or Sneddon-Wilkinson disease is a skin eruption in which concomitant systemic involvement has not been reported to our knowledge. We describe a patient suffering from SPD of 6 years duration with amicrobial inguinal lymph node suppuration and aseptic spleen ...
Subcorneal Pustular Dermatosis of Sneddon-Wilkinsondoi:10.22546/57/1919SKIN diseasesSKIN disease diagnosisDISEASES in older womenTUMOR necrosis factorsMETABOLIC syndromeETIOLOGY of diseasesJ., CostelhaA., BarrosGalicia Clínica
Intriguingly, there is a group of patients who develop a superficial neutrophilic disease very similar to Sneddon-Wilkinson disease, showing either subcorneal or intraepidermal pustule formation. However, in contrast to Sneddon-Wilkinson disease, these patients show characteristically IgA deposits on the ...
Sneddon-Wilkinson disease is a benign amicrobial pustulosis belonging to the spectrum of neutrophilic dermatoses. It is characterized by evident stereotypic clinical features, including, in most cases, pustular lesions of the trunk and prominent skin folds. This pustulosis may be...
Complete remission of skin lesions in a patient with subcorneal pustular dermatosis (Sneddon-Wilkinson disease) treated with antimyeloma therapy: Association with disappearance of M-proteindoi:10.1111/bjd.14954P.A. von dem BorneM.F. Jonkman
Methods: Human skin keratinocytes (HaCaT cells) were stimulated by polyinosinic-polycytidylic acid (poly(I:C)), which mimics viral infection, and UVB exposure. We assessed the expression of RIG-I and IFN-regulatory factor (IRF)-1 in HaCaT cells by RT-PCR and Western blot analysis. Moreover...