Today, there is renewed interest in pursuing snake-venom-based therapies. This Review focuses on the chemistry of snake venom and the potential for venom to be exploited for medicinal purposes in the development of drugs. The mixture of toxins that constitute snake venom is examined, focusing on...
Medicinal plants (natural antidotes) have been documented previously to have various constituents to inhibit snake venom enzymes. A Remedial Approach for Naja naja karachiensis Envenomation: Enzymatic Assay for Alkaline Phosphatase Activity in Extracts of Local Plants of Pakistan Studies on possible protect...
SNAKE venomFER-de-lancePLANT metabolitesMETABOLITESVENOMPHOSPHOLIPASE A2PLANT extractsThere are few scientific studies that explore the use of medicinal plants for snakebite envenoming in Central America, although plant-based therapies have been traditionally used in the region. This wo...
The venom so collected is used for producing life-saving antivenom, biomedical research and for other medicinal products.[70] The Irulas are also known to eat some of the snakes they catch and are very useful in rat extermination in the villages. Despite the existence of snake charmers, ...
Complementary to these approaches, biodiversity-driven drug discovery has been steadily explored by many medicinal chemists, biochemists and parasitologists, as a crucial part of antiparasitic drug development initiatives [25], [26]. Among the many natural sources that have been and are being ...
Snake Venom Phospholipase A2 Inhibitors: Medicinal Chemistry and Therapeutic Potential Phospholipases A2 (PLA2s) are commonly found in snake venoms from Viperidae, Hydrophidae and Elaphidae families and have been extensively studied due to th... S Marcussi,CD Sant'Ana,CZ Oliveira,... - 《...
- 《Bioorganic & Medicinal Chemistry Letters》 被引量: 56发表: 2005年 Snake venom phospholipases A2. A fluorescence study of their binding to phospholipid vesicles correlation with their anticoagulant activities. The interaction of snake venom phospholipases A2 with phospholipids has been studied by ...
Morbidity from snakebite envenoming affects approximately 400,000 people annually. Tissue damage at the bite-site often leaves victims with catastrophic life-long injuries and is largely untreatable by current antivenoms. Repurposed small molecule drugs
The article offers the author's insights on the use of snake venom in the treatment of arthritis. The author says that snake venom has been used for arthritis by the Ayuverda medical system in India through detoxification. The author cites that an Indian study shows that Indian monocellate co...
One of them is hirudin, a thrombin inhibitor from Hirudo medicinalis saliva, studied for its potential as an antithrombotic molecule (77–79). Antimicrobial Peptides Versus Enzymes Clearly snake venom peptides have the potential for practical and therapeutic use. However, enzymes and proteins are ...