In recent years, accumulating evidence suggests that the actin cytoskeleton of smooth muscle undergoes restructuring amid proliferation and migration. Disruption of actin cytoskeletal reorganization impairs the cellular processes that orchestrate smooth muscle cell growth and migration. This review will recapitul...
This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, ...
smooth muscleα-actin andcalponin. Other markers follow, also in the early pseudoglandular stage, including smooth musclemyosin heavy chain, sm-22α, anddesmin. The appearance of mature airway smooth muscle cells in developing airway walls is temporally linked to the generation of regular waves of...
Primary human aortic smooth muscle cells (HASMCs) rapidly lose expression of contractile SMC proteins when cultured in the high serum (“growth”) medium, but retain their expression in the low-serum (“differentiation”) medium24. As expected, switching cultured HASMC from the growth to differen...
A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus Ichiro Yajima1,2,3., Sophie Colombo1,2,3., Isabel Puig1,2,3, Delphine Champeval1,2,3, Mayuko Kumasaka1,2,3, Elodie Belloir1,2,3, Jacky Bonaventure1,2,3...
(mainly smooth muscle cells) are considered to be the principal reasons for the thinning fibrous cap. ACTA2+ cells were the main cellular components in the fibrous caps of stable plaques, while there were more CD68/LGALS3 positive cells in the fibrous caps of unstable plaques. Some of ...
The aim of our study was to develop a novel approach to investigating mouse detrusor smooth muscle cell (SMC) physiological activity, utilizing an acute tissue dissection technique and confocal calcium imaging. The bladder of a sacrificed adult female NMRI mouse was dissected. We used light and tr...
13.Degranulated mast cell induced by ox-LDL improves the formation of smooth muscle cell-derived foam cells肥大细胞在平滑肌细胞源性泡沫细胞形成中的作用 14.The microscopic appearance of a leiomyoma indicates that the cells do not vary greatly in size and shape and closely resemble normal smooth mu...
The microscopic appearance of the detrusor revealed a normal cellular arrangement in the groups (Figures 3(a) and 3(c)), but in the study group, marked subepithelial fibrosis and intermuscular fibrosis were seen with Masson trichrome stain compared to the control group (Figures 3(b) and 3(d...
Smooth muscle contains interdigitating thick and thin filaments, but their order is not nearly as precise as exists in striated muscle, giving rise to a ‘smooth’ versus striated appearance in the light microscope. The difference in microscopic appearance between smooth muscle and skeletal muscle ...