A diagram showing the composition of a blood vessel. Smooth muscle cells are found in the tunica media. Like a skeletal muscle, the contraction of a vascular smooth muscle is controlled by the nervous system. Unlike skeletal muscles, which are voluntarily controlled, vascular smooth muscles are i...
Smooth muscle cells are sometimes electrically coupled to allow waves of electrical activity as seen in the gastrointestinal tract or uterus. Some interesting types of channels observed in smooth muscle include BK channels, which are opened by depolarization and/or rises in intracellular Ca2+; stretch...
leading to myocardial infarction and stroke. Unraveling the origin and plasticity of various cell types that critically participate in all phases of plaque formation and destabilization is essential in understanding the pathogenesis of atherosclerosis. Smooth muscle cells (SMCs)...
The propagation of Ca~(2+) wave through gap junction in smooth muscle cell is studied as a function of electrical coupling parameter (g) modulated by Ca~(2+) level in the cell. The range of activation time of Ca~(2+) propagation with amplitude is found to increase as increase in ...
Smooth muscle cell (SMC) phenotypic modulation, primarily driven by PDGFRβ signaling, is implicated in occlusive cardiovascular diseases. However, the promotive and restrictive regulation mechanism of PDGFRβ and the role of protein tyrosine phosphatase
Arteriovenous fistulas (AVFs) are the most common vascular access points for hemodialysis (HD), but they have a high incidence of postoperative dysfunction, mainly due to excessive neointimal hyperplasia (NIH). Our previous studies have revealed a highly
Related to Smooth muscle cells:Red blood cells,Nerve cells smooth muscle n. Muscle tissue that contracts without conscious control, having the form of thin layers or sheets made up of spindle-shaped, unstriated cells with single nuclei and found in the walls of the internal organs, such as ...
In addition, we identified the potential transcription factor of driving smooth muscle cells phenotypic transformation and constructed transcriptional regulatory network. Based on the public database and quasi-time series analysis, the driving transcription factors corresponding to different phenotypic ...
Related to smooth muscle:smooth muscle antibody smooth muscle n. Muscle tissue that contracts without conscious control, having the form of thin layers or sheets made up of spindle-shaped, unstriated cells with single nuclei and found in the walls of the internal organs, such as the stomach, ...
For example, increasing the layers of RER sheets helps some cells secrete greater numbers of proteins. Conversely, cells such as neurons and muscle cells that do not secrete as many proteins may have more SER tubules. Theperipheral ER, which is the portion not connected with the nuclear envel...