smooth endoplasmic reticulum smoother smooth hound smoothing circuit smoothing consumption smoothing press smooth out smooth over smooth-spoken smooth-tongued Translations make smooth Catalan: allisar (ca) Danish: glatte, udglatte Dutch: glad (nl) maken (nl), gladstrijken (nl) Es...
Historically,smooth musclehas been of interest because of its specialized function. It lines the hollow organs, such as blood vessels and the gastrointestinal (GI) tract. Its structure is less organized than that of striated muscle and thus somewhat less amenable to biophysical experimentation. For ...
Specifically, we postulate that estrogen may have a dual regulatory effect on VSMCs function. On one hand, under normal physiological conditions, estrogen inhibits VSMCs proliferation and migration. On the other hand, under pathological circumstances, estrogen can activate the ERK pathway to promote ...
ICCs were characterized by rough endoplasmic reticulum, electron-lucent caveolae and electron-lucent intracellular vesicles. Individual ICCs tended to form contacts with neighbouring ICCs, as some cytoplasmic extensions were present between them. Further, on Fluo-4 loaded preparations, we detected numerous...
Inositol 1,4,5-tris-phosphate (IP3) binding to its receptors (IP3R) in the endoplasmic reticulum (ER) activates Ca2+ relea... Don-On,Daniel,Mak,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 208发表: 1998年 Ca2+-independent vesicular...
49and other factors30important for ICC to survive and function, the exact mechanisms that underlie these observations will need to be investigated further. The beneficial effects provided by STO cells are important during the initial phase of the smooth muscle cell culture. It is likely that other...
In CyDye-tagged fluorescent bands (A), we achieved an overall increase from 5 to 32% within the groups of membrane, membrane-associated, and extracellular matrix proteins and a corresponding reduction in intracellular proteins (cytoskeleton, cytoplasm, mitochondria, nucleus, endoplasmic reticulum, and ...
Abbreviations: N—Nucleus, nu—Nucleolus, ne—nuclear envelope, Pm—Plasma membrane, Chr—Chromatin materials, m—Mitochondria, RER—Rough endoplasmic reticulum, Arrows—Autophagic vacuoles. (* p < 0.05). Next, the expression of proinflammatory cytokine TNF-α correspondingly antioxidant enzyme GPx ...
The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex. Mol. Cell. Biol. 1997, 17, 571–583. [CrossRef] 49. McGowan, C.H.; Russell, P. Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 ...
Autophagy, as a crucial degradation process maintaining cellular homeostasis under stress conditions, has been associated with the regulation of vSMC function and the development of neointimal lesions (Lv et al., 2020). We considered the possibility that autophagy is involved in the phenotypic ...