5. Why can't I find domain X,Y or Z in my sequence? If you send the sequence, we might be able to find out why You can use SMART in two different modes:normalorgenomic.The main difference is in the underlying protein database used. InNormal SMART, the database contains Swiss-Prot,...
The protein database in Normal SMART has significant redundancy, even though identical proteins are removed. If you use SMART to explore domain architectures, or want to find exact domain counts in various genomes, consider switching to Genomic mode. The numbers in the domain annotation pages will...
两种模式可以通过SETUP菜单进行切换,通过颜色可以辨别所处的模式,示意如下 通过右上角的Search SMART按钮,可以检索该数据库,支持以下蛋白名称和domain两种检索方式。 输入uniprot或者ensembl 数据库中的蛋白ID进行检索,示例如下,根据uniprot数据库中的蛋白IDC1S_HUMAN进行检索 http://smart.embl-heidelberg.de/smart/show_...
Protein Structure, TertiaryGenomeSMART (Simple Modular Architecture Research Tool) is a web tool (http://smart.embl.de/) for the identification and annotation of protein domains, and provides a platform for the comparative study of complex domain architectures in genes and proteins. The January ...
Each domain found in a non-redundant protein database as well as search parameters and taxonomic information are stored in a relational database system. User interfaces to this database allow searches for proteins containing specific combinations of domains in defined taxa. 展开 ...
SMART (Simple Modular Architecture Research Tool) is a web tool (http://smart.embl.de/) for the identification and annotation of protein domains, and provides a platform for the comparative study of complex domain architectures in genes and proteins. The January 2004 release of SMART contains 68...
Initially, the SMART database was leveraged to discern the signaling domain, revealing two domains integral to stress response mechanisms: phosphotransferases (TYRKC) and E3 ubiquitin-protein ligase (RBR). Subsequently, UniProt IDs SM00184 and SM00219, corresponding to RBR E3 Ubiquitin and TYRKC do...
It uses precomputed orthologous groups and phylogenies from the eggNOG database (http://eggnog5.embl.de) to transfer functional information from fine-grained orthologs only. Common uses of eggNOG-mapper include the annotation of novel genomes, transcriptomes or even metagenomic gene catalogs. The ...
A cDNA was amplified by using PCR with this library diluted in 96-well-plate as templates. The sequence of this cDNA shows 83% similarity to Actin2 gene in the NCBI database (Accession No. 692696). 展开 关键词: Banana Fruit Switching mechanism at 5' end of RNA transcript cDNA library ...
This compatibility opens up avenues for researchers to explore complex membrane systems, delve into protein-membrane interactions, and gain valuable insights applicable to various biological processes and the development of therapeutics.Data availability The data that support the findings of this study are...