Case 1 A 26-year-old, healthy white woman received her first smallpox vaccination (Dryvax;, Wyeth Laboratories, Inc., PA, USA) 9months prior to presentation. By history, the vaccine site progressed through typical postvaccinia changes, but eventually developed a nodule that was cosmetically ...
Edward Jenner didn’t even develop his revolutionary cowpox-based vaccine for smallpox until 1796. The best inoculation technique at Washington’s disposal during the Revolutionary War was a nasty and sometimes fatal method called “variolation.” “An inoculation doctor would cut an incision in ...
^ a b Vaccine and Serum Evils, by Herbert M. Shelton, p. 5 ^ a b c d Hopkins DR (2002). The Greatest Killer: Smallpox in history. University of Chicago Press. ISBN 978-0-226-35168-1. Originally published as Hopkins DR (1983). Princes and Peasants: Smallpox in History. Universi...
Edward Jenner (1749-1823)The History and Effects of Smallpox, Inoculation, and Vaccination Harry Bloch, MD Author Affiliations Am J Dis Child. 1993;147(7):772-774. doi:10.1001/archpedi.1993.02160310074022 Full Text Abstract The rapid pace of vaccine development in recent decades often lead...
Four of these five CVI-78/CL subjects and the single C L / C L subject also were the only children who had a history of mild systemic symptoms after revaccination. The calf lymph vaccine used for revaccination was obtained in lyophilized form from Wyeth Laboratories and had a chorioallan-...
Berger, K., and Heinrich, W., Decrease of post-vaccinal deaths in Austria after introducing a less pathogenic virus strain, in: International Symposium on Smallpox Vaccine (R. Regamey and H. Cohen, eds.), pp. 199–203, Karger, Basel, 1973. Google Scholar Bernstein, S. S., Smallpox...
Table 2 Healthcare workers' vaccine safety concerns and self-assessed health history Full size table When asked at the end of the survey how carefully they had read the accompanying vaccine information sheet, 47% of respondents said they had read it carefully, 16% said they had read parts of...
Smallpox vaccine Smallpoxis an acute contagious disease caused byvariola virus, a member of theorthopoxvirusfamily. Prior tovaccinationagainstsmallpox, it was one of the most devastating diseases known to humanity.Smallpoxinfection killed approximately 30% of those infected. Through history, it also...
fascinating history—from variolation to development of a vaccine in the eighteenth century to complete elimination in 1977. Download references Author information Authors and Affiliations Indiana University, Bloomington, IN, USA Milton W. Taylor
The first smallpox vaccine was developed by Jenner in the late 18th century. Noticing that milkmaids who contracted cowpox (a close relative to smallpox) developed an immunity to the disease, he used the pus from cowpox lesions to create the vaccine. Approximately a century and a half later,...