The disease has a characteristic exanthem and disfigures and sometimes blinds most of the survivors. A closely related poxvirus, that of variola minor (or alastrim), causes a similar exanthem but less severe illness and the case fatality rate is 2% or less....
Case fatalityfor smallpox caused byV. majorranges between 20% and 40%. The flat and hemorrhagic forms are usually fatal.Fatality ratesin vaccinated persons are approximately 3%.Blindnessandlimb deformitiescould also besequelaefrom smallpox.V. minoris a much less severe disease and had a case-fata...
Smallpox, if used as a biological weapon, has the potential to cause widespread disease and death and could devastate a city or region.[3] A case-fatality rate of 30% was observed during smallpox epidemics in Asia. Fatality rates are higher among unvaccinated individuals. Currently, no clinic...
Case fatality rate and frequency of smallpox by type and vaccination status according to Rao case study[31] Type of disease Case fatality rate (%)Frequency (%) Unvac.Vac.Unvac.Vac. Ordinary discrete 9.3 0.7 42.1 58.4 Ordinary confluent 62 26.3 22.8 4.6 Ordinary semiconfluent 37 8.4...
This genotype was associated with case-fatality rates of less than 1%. Regardless of strain, Variola virus is capable of efficient human-to-human transmission. Secondary attack rates of 36 to 88% and 2 to 47% for unvaccinated and smallpox-vaccinated persons, respectively, led in some parts ...
with widespread lesions and case fatality rates of 15–25% in unvaccinated persons, exceeding 40% in children under 1 year. From the early 1960s to 1977, variola minor was prevalent in South America and south and east Africa; manifestations were milder, with a case fatality rate of less th...
This is because smallpox has a fatality rate of around 30% in unvaccinated individuals, according to the Centers for Disease Control and Prevention (CDC). Historically, the virus was most dangerous to women who were pregnant or people who had immune disorders. Though many of the people who ...
The case-fatality rates are about 20% to 35% among those who have not been vaccinated.10-13 Infants, pregnant women, and older adults are at higher risk of mortality from smallpox, 10-12 and there is a lower risk of death among immunized individuals.10 Smallpox reportedly caused more ...
A closely related poxvirus, that of variola minor (or alastrim), causes a similar exanthem but less severe illness and the case fatality rate is 2% or less. DOI: 10.1007/978-1-4613-3988-5_20 被引量: 1 年份: 1976 收藏 引用 批量引用 报错 分享 ...
Smallpox (also known by its scientific name, variola) was a horrible, highly infectious disease, with a case fatality-rate of 30%. In 1798, Edward Jenner, an English country doctor, published data on cowpox (or "vaccine," a term derived from the Latin for cow and increasingly preferred ...