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In certain driver subgroups, such as HER2 mutations, PFS was positively correlated with the smoking status (3.4 months in smokers versus 2 months in non-smokers; P = 0.04). Of note, the median percentage of programmed death-ligand 1 (PD-L1) expression was 0% in the HER2-mutant cohort....
41 The study determined that NSCLC patients who are positive for KRAS mutations are typically White and have a history of cigarette smoking. They also reported that age, gender, or the number of pack-years was not associated with KRAS mutation incidence. Interestingly, never smokers were more ...
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