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of one experiment (n ¼ 4). Williams's test was used to compare PCO371- or hPTH(1–34)-treated groups with vehicle-treated group; **Po0.01, ***Po0.001. In vivo experiments in OVX rats. To evaluate the effect of PCO371 on bone metabolism, we examined its effects on BMD, bone ...
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(Fig.1f). Among them, P3, named artepillin C (3, 5-diprenyl-4-hydroxycinnamic acid, APC, Fig.1g), exhibited the most potent capability to dissociate the CREB/CRTC2 complex (Fig.1f). As artepillin C has been reported to be one of the major and characteristic constituents of ...