Yolk and white areas are not mutually exclusive. In addition the points are coloured in blue if predicted as actively effluxed by P-gp (PGP+) and in red if predicted as non-substrate of P-gp (PGP−). For an interactive analysis, the user can leave the mouse over a dot to...
17allows for intuitive evaluation of passive gastrointestinal absorption (HIA) and brain penetration (BBB) in function of the position of the molecules in the WLOGP-versus-TPSA referential.The white region is for high probability of passive absorption by the gastrointestinal tract, and the yellow r...