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Shift work is a risk factor for chronic diseases such as Type 2 diabetes. Food choice may play a role, however simply eating at night when the body is primed for sleep may have implications for health. This study examined the impact of consuming a big versus small snack at night on gluco...
we identify artepillin C (APC) from propolis as an inhibitor of CREB-CRTC2 interaction. Without apparent toxicity, APC protects mice from high fat diet-induced obesity, decreases fasting glucose levels, enhances insulin sensitivity and reduces lipid levels in the serum and liver by suppressing CRE...
These multi-subunit protein complexes use energy from ATP hydrolysis to disrupt or move nucleosomes, thereby remodeling chromatin and modulating access to DNA (Narlikar et al., 2013, Petty and Pillus, 2013, Hargreaves and Crabtree, 2011, Mahmoudi and Verrijzer, 2001). We have recently found ...
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PCO371 is expected to provide three advantages: robust serum Ca control, low risk of hypercalciuria and a decrease in pill burden. However, we should bear in mind that rat skeleton is different from human skeleton, thus non-rodent animal models for studying human bone metabolism are needed to...
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