Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among elderly individuals and is recognized as a major vascular contributor to dementia, cognitive decline, gait impairment, mood disturbance and stroke. However, clinical symptoms are often highly inconsistent in nature and severity...
Cerebral small vessel disease can be identified using magnetic resonance imaging, and includes white matter hyperintensities, lacunar infarcts, cerebral microbleeds, and brain atrophy. Cerebral small vessel disease and chronic kidney disease share many risk factors, including hypertension. This study aims ...
The CHA2DS2-VASc score is a validated predictor of ischemic stroke in atrial fibrillation (AF) patients. However, data are limited on whether the CHA2DS2-VASc score is associated with subclinical brain structural changes or physical frailty among older AFpatients. We assessed the relationship ...
cerebral small vessel disease; ESUS, embolic stroke of undetermined source; WMH, white matter hyperintensity; EPVS, enlarge perivascular space; CMB, cerebral microbleed; IAP, intracranial atherosclerosis plaque; IACP, intracranial atherosclerosis complicated...
Since the retinal and cerebral small vessels share similar embryological origins, anatomical features, and physiological properties, altered retinal microvasculature might provide a new perspective on the mechanisms of cerebral small vessel disease (CSVD). Objective We aimed to evaluate retinal vessel ...
NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment... M Yao,D Hervé,N Allili,... - 《Cerebrovascular Diseases》 被引量: ...
Monogenic cerebral small-vessel diseases: diagnosis and therapy: consensus recommendations of the European Academy of Neurology. Eur J Neurol. 2020;27(6):909-927. doi:10.1111/ene.14183 PubMedGoogle ScholarCrossref 4. Joutel A, Corpechot C, Ducros A, et ...
small vessel disease in VCI are microhemorrhages. However, while computed tomography and magnetic resonance imaging are able to detect morphologic lesions, these modalities cannot determine functional consequences of the underlying pathological changes, which can be detected and quantitatively assessed by ...
Cerebral small vessel disease (SVD) is a major cause of stroke and cognitive impairment. It is estimated that 20–42% of ischemic strokes are of small vessel origin [1], and conversely, patients with stroke have a higher burden of SVD compared to the population at large [2]. In addition...
Rene´ IF de Coo6, Jan C den Hollander7, Renske Oegema1, Douglas B Gould4 and Grazia MS Mancini*,1 Familial porencephaly, leukoencephalopathy and small-vessel disease belong to the spectrum of disorders ascribed to dominant mutations in the gene encoding for type IV collagen alpha-1 (COL...