Classically, small-vessel vasculitis in the skin presents as palpable purpura (see the image below). The primary lesion is palpable due to inflammation, and purpuric due to extravasation of red blood cells, indicative of the underlying vascular damage. Less common morphologies include urticarial lesio...
Lacunar Infarcts and Small-Vessel Disease Book Title Practical Guide to Neurovascular Emergencies Pages pp 81-84 Copyright 2014 DOI 10.1007/978-2-8178-0481-1_6 Print ISBN 978-2-8178-0480-4 Online ISBN 978-2-8178-0481-1 Publisher Springer Paris Copyright Holder Springer-Verlag France Additional...
Since this first TEVG, several small-diameter cellularized vessel substitutes have been elaborated and tested with different production approaches which are presented in Fig.1. Fig. 1: Fabrication approaches to produce a small-diameter TEVG. ...
The omnigenic/polygenic view asserts that the genes in a cell form a network with highly connected core genes, with a direct role in the process/disease, and peripheral genes, which transregulate the core genes and tip the balance. Because the principles of regulation of gene expression are ...
Non-small-cell lung cancer (NSCLC) is an aggressive disease in which vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) are implicated in tumour growth, tumour resistance to radiation and chemotherapy, and disease relapse. We have investigated the anti-tumoural effects of...
Non-small-cell lung cancer (NSCLC) is an aggressive disease in which vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) are implicated in tumour growth, tumour resistance to radiation and chemotherapy, and disease relapse. We have investigated the anti-tumoural effects of...
ANG promotes blood vessel growth [104,105] and neuronal cell survival [106]. Particular isoforms of ANG display anti-microbial properties suggesting activities on microbial tRNAs [107]. Interestingly, both Ranpirnase and Amph display antiviral and anti-tumour activities, which suggested additional ...