Small vessel disease (SVD) is a pathology that affects microcirculation in the brain and can be detected by imaging techniques such as magnetic resonance and computed tomography. SVD leaves a heterogeneous phenotype of imaging markers, ranging from white matter changes to microbleeds. The pathogenesis...
小血管疾病(Small Vessel Disease),通常会导致陷窝中风(Lacunar Strokes)。心血管疾病(Cardiovascular Disease),尤其与使 … www.asaimtaiwan.org|基于6个网页 3. 小血管脑疾病 ...nfarct dementia)、单一中风引发、及小血管脑疾病(small vessel disease),后者又称宾是网格病(Binswanger’s disease)。
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among elderly individuals and is recognized as a major vascular contributor to dementia, cognitive decline, gait impairment, mood disturbance and stroke. However, clinical symptoms are often highly inconsistent in nature and severity...
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IMPORTANCE: It remains unclear if and how associations between cerebral small-vessel disease and Alzheimer disease (AD) pathology lead to cognitive decline and dementia. OBJECTIVE: To determine associations between small-vessel disease and AD pathology. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional...
CONCLUSIONS: We found WMH and lacunes to be independently associated with general cognitive function in a sample of independently living elderly. These results highlight the fact that WMH and lacunes should both be evaluated when assessing small vessel disease in relation to cognitive function. 展开 ...
Cerebral small vessel disease is a major cause of stroke and dementia, but its genetic basis is incompletely understood. We perform a genetic study of three MRI markers of the disease in UK Biobank imaging data and other sources: white matter hyperintensities (N = 42,310), fractional anis...
Molecular Imaging in the Diagnosis of Dementia due to Small Vessel Disease The diagnosis of vascular cognitive impairment (VCI) is difficult because there is no consensus on clinical criteria. Additionally, cerebral arteriosclerosis frequently is present in elderly patients and even small infarcts or whi...
Cerebral small vessel disease (SVD) encompasses progressive fibrosis/hyalinosis of the small arteries (lipohyalinosis) and arterioles (arteriolosclerosis) of the white matter (WM) resulting in ischemic WM damage. SVD is commonly assessed using a broad semi﹒uantitative (SQ) criterion. We ...
Small Vessel Disease and Alzheimer's Dementia: Pathological Considerations Current evidence suggests that the neuropathology of Alzheimer type of dementia comprises more than amyloid plaques and neurofibrillary tangles. At least a... RN Kalaria - 《Cerebrovascular Diseases》 被引量: 425发表: 2002年 Cere...