The pattern of sensitivity to AM-9022 treatment varied across the TNBC PDX panel (Fig. 6d). Notably, AM-9022 inhibited tumor growth in the CTG-0017 model (P value = 6.5 × 10−164) with evidence of TR (83% TR), resulting in 90% tumor-free mice by day 58. AM-9022 ...
Our CGH analysis did not identify any sex specific pattern inP. ornatum(Fig.4e,f). We observed genome wide hybridisation pattern of fluorescently labelled DNA on both male and female chromosomes, indicating cytologically indistinguishable genomic differentiation between the X and Y chromosomes. Fluoresc...
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Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway. Exp Cell Res. 2018;370:333–42. Article CAS PubMed Google Scholar Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini FC, Krause DS, et al. ...
[11].WOX9is involved in maintaining normal cell proliferation and preventing premature differentiation in the SAM [24].WOX13shows strong expression in mature flowers and young siliques, and it plays a role in fruit development [25].WOX14is mainly expressed in vascular tissue and is involved in...
In most angiosperm anthers, four lobes surround the connective tissue and the central vasculature. Within each lobe, layers of sub-epidermal somatic cell types (endothecium, middle layer, and tapetum) encircle the centrally located archesporial cells (AR cells), which later become pollen mother ...
Accumulated evidence has shown that plasma can be generated and play an increasingly important role in various applications at room temperature, such as blood coagulation, wound healing, and tissue and device sterilization [1]. Furthermore, using endoscopic effect of non-thermal atmospheric pressure ...
Spruce homogenate contained remnants of the tissue and residual cells (Figure 2A (S raw)), while the supernatant of the ultracentrifugation contained clusters of small, bilayer membrane-enclosed vesicles with radii below 50 nm (Figure 2C (S2 100 nm) and (Figure 2B (S2 10 nm)). SCPs were...
Procoagulant extracellular vesicle (EV) concentrations have been found to increase in several diseases, but the relative contribution of small (sEVs) and large (lEVs) EVs to plasma prothrombotic potential is poorly defined. Our study shows for the first time that the concentration of tissue factor...
Comparing the presence or absence of these miRNA families with the free-living Schmidtea mediterranea, we found 13 conserved miRNAs are lost in E. granulosus, most of which are tissue-specific and involved in the development of ciliated cells, the gut and sensory organs. Finally, GO enrichment ...