In addition, human 14 C radioactive trials of most of these TKIs have not been conducted, and the data of drug-drug interactions in clinic are also absent, which indicate our deficiency compared to the international regular approaches in metabolic research. 展开 ...
Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan M. Douglas et al., "Small- molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan," Nature Communications, vol. 8, ...
p pBackground/p pThe ability to regulate metabolism is a fundamental process in living systems. We present an analysis of one of the mechanisms by which metabolic regulation occurs: enzyme inhibition and activation by small molecules. We look at the network properties of this regulatory system an...
Alpha-ketoglutarate affects murine embryo development through metabolic and epigenetic modulations Some ideas: α- Ketoglutarate is one of the few common anti-aging supplements. It is really a molecule that achieved life prolonging effect in mouse experiments. It is suggested that anti-aging enthusiasts...
The molecular targets and mechanisms of propolis ameliorating metabolic syndrome are not fully understood. Here, we report that Brazilian green propolis reduces fasting blood glucose levels in obese mice by disrupting the formation of CREB/CRTC2 transcri
All polymer solar cells (all-PSCs) consisting of polymer donors (pDs) and polymer acceptors can be produced into flexible and large-area devices such as using low-cost materials and solution-processible printing technologies. All-PSCs possess advantages in comparisons with small-molecule acceptor ...
journal of clinical endocrinology & metabolic disorders research article a small molecule induces oligodendrogenesis leading to myelin sheath repair 来自 dx.doi.org 喜欢 0 阅读量: 20 作者:N Sh,YJJ Clin,E Metabdisord,Jcmd-,SH Nye,JG Yarger ...
metabolic disorders small-molecule inhibitors triacylglycerides ASJC Scopus subject areas Drug Discovery General Pharmacology, Toxicology and Pharmaceutics Molecular Medicine Biochemistry Pharmacology Organic Chemistry UN SDGs This output contributes to the following UNSustainable Development Goals (SDGs) ...
perforans, a pathogen of bacterial spot of tomato (Solanum lycopersicum L.) as well as the metabolic changes in X. perforans following treatment with the small molecule carvacrol. Bacterial spot of tomato is a significant problem in almost all tomato-growing regions and is favored by warm ...