However, the model is not optimal because mice develop mostly small intestine tumors [224]. Tumor number in female ApcMin/+ mice at 4–5 weeks of age is not affected by 10 weeks of treatment with 1,25(OH)2D3 or its analogs 1,25(OH)216-ene-19-nor-24-oxo-D3 (Ro 26-9114)....
intestinal transit data of a liquid meal labeled by a nonabsorbable marker,14C-polyethylene glycol, it is apparent that the proximal small intestine has a short exposure time to the rapidly advancing isotope bolus and is therefore responsible only for the modest Mg absorption observed during the ...
Intestine, SmallJejunumEndocrine GlandsEpithelial CellsMucusAutoradiographyCell DifferentiationOne hour after injection of 3H-thymidine, labeled mucous cells were not observed below position 5. Only later did they appear in lower positions and not until 4 days after injection were they observed in ...
g, Small intestine samples were obtained from mice in experiment Fig. 6b. H&E and Alcian blue staining was performed on processed, sliced samples. Scale bar: 200 μm. h, Quantification of Alcian blue staining results from (g). Data represent mean ± SEM. n = 12 fields from...
The gut is a major energy consumer, but a comprehensive overview of the adaptive response to fasting is lacking. Gene-expression profiling, pathway analysis, and immunohistochemistry were therefore carried out on mouse small intestine after 0, 12, 24, an
We next sought to characterize monocyte development in the normal and inflamed small intestine. Unlike the well-established different models of experimental colitis, only few mouse model of small intestinal sterile inflammation have been reported. In this study, we adopted a model of small intestinal...
While the signal of both tracers was equally good at detecting tumor-bearing adrenals, the background signal was lower for [18F]-LMI1195 in organs such as liver, lung, small intestine and bone, a feature that could be relevant for the imaging of PPGL metastases or small primary tumors. ...
Upper gastrointestinal (GI) disorders and abdominal pain afflict between 12 and 30% of the worldwide population and research suggests these conditions are linked to the gut microbiome. Although large-intestine microbiota have been linked to several GI di
Therefore, cells with EPX activity were labeled by incubating frozen sections of intestine for 8–10 min at room temperature with FITC-conjugated tyramide (obtained from NEN Life Science Products and diluted 1:100 in 1 × amplification diluent from the same manufacturer). Following 3 washes in ...
Polydatin ameliorates injury to the small intestine induced by hemorrhagic shock via SIRT3 activation-mediated mitochondrial protection. Expert. Opin. Ther. Targets 20, 645 (2016). Article CAS PubMed Google Scholar Han, B. et al. A simple disc degeneration model induced by percutaneous needle ...