insertiondeletionselectionsite frequency spectrumSNPAlthough lines of evidence suggest that small insertions and deletions differ in their mechanisms of formation, there remains the debate on whether natural selection acts differently on the two indel types. Currently available personal genomes and the 1000...
Detection and characterization of small insertion and deletion genetic variants in modern layer chicken genomes.doi:10.1186/s12864-015-1711-1Small insertions and deletions (InDels) constitute the second most abundant class of genetic variants and have been found to be associated with many traits and ...
A. Krassovitskiy, Yu. Rogozhin, S. Verlan, Computational Power of P Systems with Small Size Insertion and Deletion Rules, In:Proc of CSP08 , pp. 137-148, 2008.A.Krassovitskiy, Y.Rogozhin, S.Verlan: Computational Power of P Systems with Small Size Insertion and Deletion Rules. In:...
AZD-7762, a specific inhibitor of checkpoint kinase CHEK1, also enhanced insertion efficiency by 2.7-fold. VE-822 and AZD-7762 did not significantly increase the cell proliferation rate of hPSCs, suggesting that VE-822 and AZD-7762 can increase knockin efficiency not through promoting cell ...
More single‐nucleotide mutations surround small insertions than small deletions in primatesdoi:10.1002/humu.22085insertiondeletionselection... S Huang,T Yu,Z Chen,... - 《Human Mutation》 被引量: 6发表: 2012年 Characteristics of mutations in the p53 gene of oral squamous-cell carcinomas associat...
Automating resequencing-based detection of insertion-deletion polymorphisms. Among these variants, the most common are small indels ( approximately 1-30 bp). Identifying and genotyping indels using sequence traces obtained from ... TR Bhangale,M Stephens,DA Nickerson - 《Nature Genetics》 被引量: ...
28.12% for 1-bp deletion on the left side of the break (termed Del1|0), 16.13% for 7-bp deletion on the right side of the break (Del0|7), and 13.87% for insertion of 1A at the break (Ins1A); Atm had two (23.81% for D6|0 and 20.07% for Ins1C), and Rb1 had none in...
英文名称:PYX-ASC-CAPN15(MOUSE) (small insertion and small deletion) 英文同义词:PYX-ASC-CAPN15(MOUSE) (small insertion and small deletion) CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览PYX-ASC-CAPN15(MOUSE) (small insertion and small deletion)国外供应商中国供应商...
Small insertion/deletions (InDels) and SNVs were detected using the GATK workflow (https://github.com/gatk-workflows/broad-prod-wgs-germline-snps-indels)16. Briefly, gVCF files were generated using GATK HaplotypeCaller via the “-ERC GVCF” option. To produce the final multisample VCF, all gV...
Overexpression, amplification and mutations ofHER2can be found in NSCLC, which are identified in 3–38%, 3% and 1–4% of patients, respectively [66]. The most frequent mutations are insertions in exon 20 (the tyrosine kinase domain), with the insertion/duplication of the four amino acids ty...