These can be accompanied by hemorrhagic foci seen on susceptibility-weighted imaging, located between the clusters of dPVS. Most, but not all patients, have lacunes and extensive confluent periventricular and deep white matter hyperintensities. Notably, in contrast to cerebral amyloid angiopathies, ...
Considerable overlap exists between the risk factors of dementia and cerebral small vessel disease (SVD). However, studies remain limited to older cohorts wherein pathologies of both dementia (e.g. amyloid) and SVD (e.g. white matter hyperintensities) al
Micro bleeds are visible small (generally 2–5 mm in diameter) area of signal void on T2-weighted gradient-echo MRI, resulting from paramagnetic properties of focal deposits of hemosiderin-containing macrophages [52,53]. These perivascular hemosiderin masses are foci of the earlier hemorrhagic event...