Vesicles that are coated by coat protein complex II (COPII) are the primary mediators of vesicular traffic from the endoplasmic reticulum to the Golgi apparatus. Secretion-associated Ras-related GTPase 1 (SAR1) is a small GTPase that is part of COPII and, upon GTP binding, recruits the other...
Secretion-associated and ras-related protein 1 (Sar1) is a small GTPase that plays an important role in the transport of protein coated with coat protein complex II vesicles. However, its alternative roles in the biological processes of Procambarus clarkii remain unclear. Here, a sar1 gene (na...
SAR1A (GTP-binding Protein SAR1a, COPII-associated Small GTPase, Masra2, SAR1, SARA, SARA1) (HRP) 中文名: 中文别名: CBNumber: CB04973780 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 SAR1A (GTP-binding Protein SAR1a, COPII-associated Small GTPase, Masra2, SAR1...
Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat protein)-coated vesicles. Our data suggest that chylomicrons, ... B Jones,EL Jones,SA Bonney,... - 《Nature...
In the GTP bound state, Sar1-GTP promotes the assembly of the COPII coat on endoplasmic reticulum (ER) membranes, whereas Arf proteins promote the assembly of various coats (COPI and clathrin⧸adaptators) on Golgi and plasma membranes.7, 8 These protein coats are made by the assembly of ...
17 SAR itself functions in cargo selection and export of proteins from the endoplasmic reticulum to the Golgi via the cytosolic coat protein complex II (COPII) secretory pathway. It has been reported that several Ras superfamily members participate in hematopoietic cell proliferation and differentiation...
In yeast, a small GTPase (190aa) that controls the assembly of the coat protein complex II (COPII) that surrounds vesicles that are involved in export from the ER. The Sar1p-GTP complex initiates membrane curvature during vesicle biogenesis. The human homologue is SAR1 (SAR1A ...