Garris et al. demonstrated that the successful anti-tumor immune response of PD-1 inhibitors depends on the interaction between T cells and DCs [57]. LAMP3+DCs are a subset of mature DCs derived from cDC1 and cDC2, which can migrate from tumors to LNs and initiate antigen-specific immune...
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TFF3 has been identified as a novel biomarker to distinguish between lung adenocarcinoma (ADC) and lung squamous-cell carcinoma (SCC). Herein, we determined the oncogenic functions of TFF3 and demonstrated the potential of pharmacological inhibition of TFF3 in lung ADC using a novel small-molecule ...
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During this time, only a few tetraploid and diploid genotypes were involved in this allopolyploid event to form primitive hexaploid wheat. Currently, it is generally believed that bread wheat evolved from a few primitive hexaploid individuals. Afterwards, the bottleneck effect of intensive selection ...
1. Shh signaling pathway initiated LNM through LYVE-1-dependent lymphangiogenesis [76]. Overexpressed STAT3 was an independent LN micrometastasis risk factor and promoted micrometastasis in early-stage NSCLC [77]. Similarly, the expression of SCC-S2 was also linked with LNM in associated analysis ...
Hypervariable region 1 gene HV2 : Hypervariable region 2 gene IQR: Interquartile range MSP: Methylation sensitive PCR mtDNA: Mitochondrial DNA NSCLC: Non-small cell lung cancer ROC: Receiver operating characteristic RQ: Relative quantitation SCC: Squamous cell carcinoma SCLC: Small cell...
Emotional distress (ED), commonly characterized by symptoms of depression and/or anxiety, is prevalent in patients with cancer. Preclinical studies suggest that ED can impair antitumor immune responses, but few clinical studies have explored its relation
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Claims: 1. A method comprising: transmitting, by a wireless device in a radio resource control, RRC, idle state or RRC inactive state, to a base station, a message comprising: first data associated with a small data transmission, SDT, procedure; and an RRC request message; and while the ...