Separation of small cell lung carcinoma (SCLC) from nonsmall cell lung carcinoma (NSCLC) is a critical distinction to be made in the diagnosis of lung cancer. However, the diagnosis of SCLC is most commonly made on small biopsies and cytologic specimens, and practicing pathologists may not be...
Treatment of Extensive-Stage Small-Cell Lung Cancer (Small-Cell Lung Cancer That Remains Incurable With Current Treatment Options) Combination chemotherapy treats people with extensive-stage small-cell lung cancer. Currently, the combination of cisplatin or carboplatin and etoposide (PE) is the most wi...
Small-cell lung cancer is most often linked to paraneoplastic syndromes, a group of symptoms that happen when the tumor makes hormone-like chemicals. Types of Small-Cell Lung Cancer There are two types of SCLC: Small-cell carcinoma (also called oat cell cancer) Combined small-cell carcinoma Th...
Emerging advances in defining the molecular and therapeutic landscape of small-cell lung cancer Traditionally, patients with small-cell lung cancer (SCLC), a malignancy with a dismal prognosis, have had limited treatment options. Over the past few years, advances in the molecular characterization of...
Small cell lung cancerEtoposideCisplatinIrinotecanTopotecanThoracic radiation therapyProphylactic cranial irradiationSmall cell lung cancer (SCLC) is a malignant epithelial tumor that occurs almost exclusively in smokers. It accounts for approximately 13% of lung cancer diagnoses in the United States annually...
Small-Cell Lung Cancer Prognosis The success of treatment depends on the stage of small-cell lung cancer. Unfortunately, in most people with small-cell lung cancer, the disease has already spread to other organs of the body by the time it is diagnosed. That shortens life expectancy. ...
SCLC is further divided into two categories: oats-cell cancer [bronchial epithelial cells develop a hostile malignancy neuroendocrine (NE) tumor] and cSCLC (combined small-cell lung cancer and nonsmall cell lung cancer). 2.1.1 Oats-Cell Carcinoma When viewed under a microscope, these canc...
Small cell lung cancer (SCLC) represents 15% of lung cancers and is characterized by early dissemination, development of chemoresistance and a poor prognosis. A host of diverse drugs failed invariably and its mechanisms of global chemoresistance have not been characterized so far. SCLC represents the...
It belongs to undifferentiated carcinoma, and its pathological types include oat cell type, intermediate cell type and mixed oat cell type. 1/5 of lung cancer patients belong to this type. Small cell lung cancer is a highly malignant tumor. Its biological behavior is bad and its prognosis is...
Prognostic factors in small cell lung cancer (SCLC)doi:10.1016/0169-5002(89)90201-8Carcinoma/non-small-cell lungPrognosisTumor markers/biologyCarcinoembryonic antigenAntigen Cyfra21-1Objective To investigate the prognostic factors in non small cell lung cancer (NSCLC) at stage Ⅲ and Ⅳ and ...