Small-cell lung cancers (SCLCs) initially respond to chemotherapy, but are often resistant at recurrence. The non-steroidal anti-inflammatory drug indomethacin is an inhibitor of multidrug resistance protein 1 (MRP1) function. The ...
Small-cell carcinoma (also called oat cell cancer) Combined small-cell carcinoma They’re named for the kinds of cells found in each cancer and what they look like. Small-Cell Lung Cancer Causes Smoking is a cause of most lung cancers. Small-cell lung cancer is diagnosed most often in hea...
Treatment of Extensive-Stage Small-Cell Lung Cancer (Small-Cell Lung Cancer That Remains Incurable With Current Treatment Options) Combination chemotherapy treats people with extensive-stage small-cell lung cancer. Currently, the combination of cisplatin or carboplatin and etoposide (PE) is the most wi...
Small cell lung cancerTargeted therapiesRadiationSmall cell lung cancer (SCLC) accounts for about 10% to 15% of all lung cancers. It is characterized by its rapid doubling time, high rate of dissemination, and increased sensitivity to chemotherapy and radiation. Although the incidence of SCLC has...
1.2 Small cell lung cancer The main forms of lung cancer include small cell lung cancer (SCLC) [3] and non-small cell lung cancer (NSCLC) [2]. Small cell lung cancer is an aggressive disease that accounts for 10–15% of all lung cancers. Metastases to regional lymph nodes or d...
small-cell lung cancer immunotherapy PD-L1 tumor microenvironment immunophenotype Introduction Small-cell lung cancer (SCLC) comprises about 15% of all new lung cancers and smoking is strongly associated with the risk of developing it. Although the incidence is higher in males, the incidence gap bet...
1.The other 75 per cent of lung cancers consist of a variety of "non-small cell cancers".其余75%的肺癌属于各种“非小细胞肺癌”。 2.hsa-miR-125a-5p Enhances Invasion Ability in Non-Small Lung Carcinoma Cell Lineshsa-miR-125a-5p促进非小细胞肺癌细胞侵袭 3.The Study of CD44s Expression ...
Surgery plays little, if any, role in the treatment of small-cell lung cancer because almost all cancers have spread by the time they are discovered. The exceptions are the relatively small number of people (less than 15%) who get diagnosed at a very early stage of the disease, when the...
Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and transcriptomic heterogeneity. Subtypes based upon predominant transcription factor expression have been defined that, in mouse models and cell lines, exhibit potential differential therapeutic vulnerabilities, with epigenetically distin...
Small cell lung cancer: Have we made any progress over the last 25 years? Oncologist. 2007; 12 :1096–1104.Lally BE, Urbanic JJ, Blackstock AW, Miller AA, Perry MC. Small cell lung cancer: have we made any progress over the last 25 years? Oncologist. 2007; 12 :1096–1104. doi:...