While initially very responsive to both chemotherapy and radiation therapy, the majority of patients will have recurrent disease or become refractory to treatment. The 5-year survival of patients with small cell lung cancer is only 5%. The staging of small cell lung cancer is divided into ...
Robert E. WittesMedicine BranchSeminars in Surgical OncologyWittes RE. Small-cell lung cancer: an overview of issues in therapy. Sem Surg Oncol 1993;9:127-34Wittes RE. Small-cell lung cancer: an overview of issues in therapy. Semin Surg Oncol. 1993 Mar-Apr; 9 (2):127–134....
在初步诊断为广泛期SCLC时,18%的患者有脑转移且2年后增至约80%。EORTC(European Organization for Research and Treatment of Cancer)的一项研究,将对化疗有反应的患者随机化分为2组,接受PCI或不接受PCI,发现PCI治疗组1年生存率为27.1%,未接受PCI者为13.3%。[49]在该研究中,PCI不仅减少脑转移的发生率也提高无...
Ginsberg RJ. Surgery and small cell lung cancer—an overview. Lung Cancer 1989;5:232–236.Ginsberg RJ (1989) Surgery and small cell lung cancer: an overview. Lung Cancer 5:232–236Ginsberg RJ.Surgery and small cell lung cancer-an overview. Lung Cancer . 1989...
Small-Cell Lung Cancer Treatment Your treatment plan will depend on several things, including how far your cancer has spread, your overall health, and what you prefer. Your doctor will recommend one or more of these treatments: Chemotherapy.You get drugs through an IV or by mouth to kill can...
small cell lung cancer; treatment Abstract: Lung cancer was relatively uncommon at the turn of the 20th century, and has increased in prevalence at alarming rates, particularly because of the augmented trend in smoking, so that it is now the most common cause of cancer death in the world. ...
So, it's really a whole new sort of subculture within drug development for lung cancer, and for that reason, it's a substantive step forward. Question:What are the implications of some of these new drugs in non–small cell lung cancer on treatment practice for this ...
Prophylactic Cranial Irradiation Overview Collaborative Group. N Engl J Med 1999; 341: 476 - 484. CrossRef Lassen U, Hansen HH. Surgery in limited stage small cell lung cancer. Cancer Treat Rev 1999; 25: 67 - 72. CrossRef Meyer JA. Indications for surgical treatment in small cell ...
Small-Cell Lung Cancer Treatment Some of the most commonly used combinations of medications used for SCLC are carboplatin (Paraplatin),cisplatin(Platinol- AQ),cyclophosphamide(Cytoxan),docetaxel(Taxotere),doxorubicin(Adriamycin,Rubex),etoposide(Vepesid),irinotecan(Camptosar), lurbinectedin (Zepzelca)...
Navigating treatment combinations in small-cell lung cancer The ETER701 trial demonstrates that a four-drug regimen, involving the addition of anti-angiogenesis therapy to immuno-chemotherapy, improves survival outcomes for extensive-stage small-cell lung cancer — but is more indeed better when it co...