Small cell lung cancer (SCLC) is one of the two major types of lung cancer. It is named because the cells appear small and round under the microscope. Facts You Should Know About Small-Cell Lung Cancer When cells of the lung start to undergo a degenerative transformation in appearance and ...
Small-cell lung cancer (SCLC) is a deadly cancer associated with smoke exposure that has neuroendocrine (NE) cell properties and is pathologically, molecularly, biologically and clinically very different from other lung cancers. While most patients with SCLC respond initially to cytotoxic therapy, almo...
small cell lung cancertreatment-related toxicitiesUntil recently, the treatment of small cell lung cancer (SCLC), a malignancy classically described as having a robust response to first-line therapy with near-universal recurrence, has remained relatively unchanged. Advancements in the management of SCLC...
Objective and study design: Limited-disease small cell lung cancer (LD-SCLC) is initially very sensitive to both radiotherapy and chemotherapy. However, the 5-year survival is generally only 10–15%, with most patients failing with therapy refractory relapses, both locally and in distant sites....
Non-small-cell lung cancer (NSCLC) is one of the most frequent cancer types and is responsible for the majority of cancer-related deaths worldwide. The management of NSCLC has improved considerably, especially in the past 10 years. The systematic screening of populations at risk with low-dose...
Notch signaling pathway is actively involved in the NE differentiation, NE plasticity, cell proliferation, tumor subtype shift and other characteristics such as EMT and chemoresistance of SCLC. Abbreviations: SCLC, small cell lung cancer; PNEC, pulmonary neuroendocrine cell; NE, neuroendocrine; EMT, ...
To determine the pharmacodynamic mechanism underlying Cordyceps sinensis relief in a murine model of non-small cell lung cancer (NSCLC). We created a murine model of NSCLC and studied the potential molecular mechanism by which C. sinensis relieved NSCLC
In 2007 theFood and Drug Administrationin the United States approved a newsmallpox vaccine, the only new vaccine for smallpox to be approved since 1931. The new vaccine, calledACAM2000, is produced using basic cell-culture techniques that allow it to be made quickly and in sufficient quantity...
This cohort study evaluates trends in survival after immune checkpoint inhibitor therapy in patients with advanced non–small cell lung cancer by age.
Association between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer Yue Zeng, Chun-Hong Hu, Yi-Zheng Li, Jian-Song Zhou, Shu-Xing Wang, Meng-Dong Liu, Zhen-Hua Qiu, Chao Deng, Fang Ma, Chun-Fang Xia, Fei Liang, Yu-...