Limited small-cell lung carcinoma: High complete response rate and survival with short intensive chemotherapy and extensive irradiation. Results of a pilot studySixteen patients with limited small-cell lung carcinoma (SCLC) were treated with three monthly courses of intensive chemotherapy (cisplatin: 40...
PD-1 inhibition: PD-1 is another protein on the surface of T cells that helps keep the body's immune reaction in check. PD-1 attaches to another protein called PDL-1 and stops the T cell from killing the cancer cell. PD-1 inhibitor drugs attach to PDL-1 and allow the T cells to ...
Small cell lung cancer (SCLC) remains a deadly form of cancer, with a 5-year survival rate of less than 10 percent, necessitating novel therapies. Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncofetal protein that is emerging as a therapeutic target and is co-expressed wi...
In adult patients, small cell carcinoma and poorly differentiated small cell angiosarcoma also become considerations. It is with the poorly differentiated variants of E-RMS that immunohistochemical analysis proves to be most helpful. Rhabdomyosarcoma expresses striated muscle markers in a cumulative and ...
Cell 150, 1121–1134 (2012). Article CAS PubMed PubMed Central Google Scholar Lam, V. K. et al. Targeted tissue and cell-free tumor DNA sequencing of advanced lung squamous-cell carcinoma reveals clinically significant prevalence of actionable alterations. Clin. Lung Cancer 20, 30–36.e33 ...
Long-term survival and prognostic factors of five- year survivors with complete resection of non-small cell lung carcinoma. J Thorac Cardiovasc Surg. 2003;126(2):558-562.Okada M, Nishio W, Sakamoto T, Harada H, Uchino K, Tsubota N. Long-term survival and prognostic factors of five-year ...
Objective response rate OS: Overall survival CI: Confidence interval HR: Hazard ratio References Myall NJ, Das M. Advances in the treatment of Stage III Non-Small Cell Lung Cancer. Clin Chest Med. 2020;41(2):211–22. Article PubMed Google Scholar Godeau D, Petit A, Richard I, ...
Consolidation durvalumab improved survival across subgroups of patients with limited-stage small cell lung cancer based on factors associated with prior prophylactic cranial irradiation and concurrent chemoradiotherapy use. Among patients with prior PCI in the durvalumab and placebo arms, the media...
Primary small cell carcinoma of the endometrium is a rare disease that can only be diagnosed at an advanced stage, and thus has a poor prognosis. In this study, the clinicopathologic characteristics of endometrial small cell carcinoma are described and the survival outcomes are discussed. Materials...
- 1994 - 178 - www.sciencedirect.comdoi:10.1016/0169-5002(94)94461-XELSEVIERLung Cancer