CMB were identified on SWI following the Microbleed Anatomical Rating Scale (MARS) [23]. Suspected CMB were cross-validated on T1w and T2w scans to exclude CMB ‘mimics’. In instances of uncertainty, CMB were labelled as ‘possible CMB’—this includes situations whereby CMB cannot be ...
microbleedTo assess whether neuroimaging markers of chronic cerebral small vessel disease (cSVDm) influence early recovery after acute ischemic stroke (AIS). Retrospective analysis of patients diagnosed with AIS and included in the Spanish Neurological Society Stroke Database. (1) Brain MRI performed ...
All subjects underwent 3.0-Tesla brain MRI (Intera; Philips Medical Systems, Best, Netherlands), including susceptibility-weighted imaging, fluid-attenuated inversion recovery imaging (FLAIR), and T1-/T2-weighted imaging, obtained with the spin-echo technique. The repetition time for the T2-images w...
Overview of methodology.aCerebral small vessel disease (SVD) was quantified on 3T MRI using four imaging markers: white matter hyperintensities, lacunes, enlarged perivascular spaces, and cerebral microbleeds.bMidlife risk factors were classified into two categories: non-modifiable (inherited) risk vs. ...
Brain imaging acquisition for LBC1936 has been described previously in detail [24]. All subjects were scanned on the same 1.5T GE Signa HDx scanner operating in research mode. The SVD score components were ascertained from axial T2, T2*, fluid-attenuated inversion recovery (FLAIR) and T1-weigh...
In particular, higher levels of Aβ40/Aβ42 were significantly associated with increased lacunar and microbleed counts, as well as increased WMH volume and poorer cognition [6]. However, low plasma Aβ42 was associated with a higher risk of extensive WMH progression over the follow-up of ...
the images show cerebral microbleed on SWI, white matter hyperintensities on FLAIR, lacunar infarction on FLAIR, and enlarged perivascular space of basal ganglia on T2WI. Abbreviations: SWI: susceptibility weighted imaging; FLAIR: fluid-attenuated inversion recovery imaging; T2WI: T2-weighted imaging. ...
In the study, Assessment of Baseline CSVD Burden measured WMH volume, lacune count, and microbleed count at baseline as CSVD markers. In analysis, baseline age predicted WMH progression. There was also a significant association between WMH volume during 14 years of follow-up. The yearly mean ...
weighted images. WMHs were graded using the Age-Related White Matter Changes (ARWMC) scale [29]. Cerebral microbleeds (CMBs) were identified as small focal rounded hypointense lesions, graded based on susceptibility-weighted imaging sequences using the Brain Observer MicroBleed Scale [30]. Medial...