1.超窗问题,要先区分开是受COVID-19影响还是本身PD/AE影响,要上报PD;treatment grp&control grp对于发生超窗的probability应该是相同的和属于MAR,后期可通过imputation/增加sensitivity analysis,相应看看你们project team的意见修改protocol和SAP 2.补发药物不需要揭盲吧,参考DTP...
【3】Nakazawa, K. & Sapkota, K. The origin of NMDA receptor hypofunction in schizophrenia.Pharmacol. Ther. 205, 107426 (2020). 【4】Südhof, T. C. Synaptic neurexin complexes: a molecular code for the logic of...
or uniform, and the answer is simple. You see, perfectionism is an attitude developed in the small things and then applied to the larger job. So basically, if you can't get the little things right, you're going to fail when it counts...