SM-102 is the only ionizable amino cationic lipid currently clinically approved for RNA therapeutics and can be used to synthesize lipid nanoparticles (LNPs). It shows potential in the development of LNPs for the delivery of mRNA-based vaccines. 体外活性 方法:研究了 SM-102 对两种内分泌细胞(大...
SM-102 is an ionizable lipid used in lipid nanoparticles (LNPs). LNP compositions have proven effective as transport vehicles into cells and/or intracellular compartments for biologically active substances such as small molecule drugs, proteins and nucleic acids.SM-102——一种专有磷脂,是构成纳米颗粒...
SM102(CAS:2089251-47-6)是mRNA疫苗组分的热门脂质。这种脂质用于这些疫苗的脂质纳米颗粒(lipid nanoparticles, LNP)制剂中,以帮助递送和保护mRNA分子,并且促进其进入人体细胞。 SM-102是一种可电离的阳离子氨基脂质,它有助于形成一种包裹mRNA的小球,这种小球被称为脂质纳米颗粒。这些纳米颗粒通过模拟病毒的方式帮助m...
SM-102 is an ionizable amino lipid utilized in the synthesis of lipid nanoparticles (LNPs)[1]. It exhibits promise in the creation of LNPs dedicated to the transportation of mRNA-based vaccines[2].产品描述SM-102是一种可电离的氨基脂质，用于合成脂质纳米颗粒（LNP）[1]。它在创造专门用于运输基于...
SM-102 is an ionizable lipid used in lipid nanoparticles (LNPs). LNP compositions have proven effective as transport vehicles into cells and/or intracellular compartments for biologically active substances such as small molecule drugs, proteins and nucleic acids. SM-102——一种专有磷脂,是构成纳米颗...
SM-102 is the only ionizable amino cationic lipid currently clinically approved for RNA therapeutics and can be used to synthesize lipid nanoparticles (LNPs). It shows potential in the development of LNPs for the delivery of mRNA-based vaccines. ...
SM-102 是一种可电离的氨基脂质,可用于形成脂质纳米颗粒 (LNPs)。SM-102 有潜力用于脂质纳米颗粒递送 mRNA 疫苗药物。Moderna已经规模化生产。 SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles.1 Administration of luciferase ...
SM102(CAS:2089251-47-6)是mRNA疫苗组分的热门脂质。这种脂质用于这些疫苗的脂质纳米颗粒(lipid nanoparticles, LNP)制剂中,以帮助递送和保护mRNA分子,并且促进其进入人体细胞。 SM-102是一种可电离的阳离子氨基脂质,它有助于形成一种包裹mRNA的小球,这种小球被称为脂质纳米颗粒。这些纳米颗粒通过模拟病毒的方式帮助...
[3]. Cho HY, et al. Effective Perturbations on the Amplitude and Hysteresis of Erg-Mediated Potassium Current Caused by 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6(undecyloxy)hexyl]amino]-octanoate (SM-102), a Cationic Lipid. Biomedicines. 2021 Oct 1;9(10):1367. ...
阳离子脂质体SM102(cationic lipid SM102)是一种常用于药物递送系统中的阳离子脂质。 阳离子脂质体是由带正电荷的脂质构成的纳米颗粒系统,用于有效地传递药物或遗传物质到细胞内。SM102是其中一种常见的阳离子脂质,其化学名为(2S)-2,3-di(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate。