Antibodies to Sm and RNP. Prognosticators of disease involvement. Arthritis Rheum 1983; 26: 848.Munves EF, Schur PH. Antibodies to Sm and RNP: prognosticators of disease involvement. Arthritis Rheum. 1983;26:848.Munves EF, Schur PH (1983) Antibodies to Sm and RNP. Prognosticators of ...
参考文献 1.Migliorini P, Baldini C, Rocchi V, et al. Anti-Sm and anti-RNP antibodies[J]. Autoimmunity,2005,38(1):47-54 2.Will CL and Lührmann R. Spliceosomal UsnRNP biogenesis,structure and function[J].Curr Opin Cell Biol,2001,13(3):290-301 END...
由于Sm和RNP是同一分子复合物中的不同抗原位点,因此二者常一同阳性,抗Sm抗体出现提示SLE患者更易出现肾脏受累。病毒感染在SLE的发病中具有重要地位,抗Sm抗体的产生可能与EB病毒感染相关。 参考资料: [1]Migliorini P,Baldini C,Rocchi V,Bombardieri S.Anti-Sm and anti-RNP antibodies.Autoimmunity.2005 Feb;3...
抗可溶性抗原(ENA)抗体是一类识别包括Sm、nRNP(主要成分是U1RNP)、SSA、SSB、Scl-70、Jo-1、核糖体P蛋白等在盐水中可溶解抗原的自身抗体。目前临床常规最常检测的抗ENA抗体包括抗Sm抗体、抗SSA/Ro抗体、抗SSB/La抗体、抗rRNP抗体和抗ScL-70抗体和抗Jo-1...
英文名称:Anti-mouse small ribonucleoprotein / Sm antibodies (snRNP / Sm) ELISA kit 分子式:电询 纯度:99 % 产地:进口/国产 品牌:钰博生物 包装规格:96t/48t 货号:yb-E11760 别名:电询 小鼠抗小核糖核蛋白/Sm抗体(snRNP/Sm)检测试剂盒其基本原理是把抗原或抗体在不损坏其免疫活性的条件下预先结合到某种...
Eighty-two patients with systemic lupus erythematosus (SLE) were investigated for the presence and significance of serum antibodies to Extractable Nuclear Antigen (ENA) and its major components, RNP, Sm and SS-B (or Ha). The counterimmun... B Clotet,J Guardia,C Pigrau,... - 《Scandinavian...
猪胸腺ENA中Sm与RNP抗原活性的研究 In this paper, Sm and RNP activities of the ENA extracted from pig thymus are investigated. Using counterimmunoelectrophoresis (CIE), when the pig thymus ENA were used as antigens, the positivities of anti-Sm and anti-RNP antibodies in t... 张明,徐文严,...
Patients with systemic lupus erythematosus (SLE) often possess antibodies against two nuclear antigens, designated "Sm" and "RNP". The exact relationship between Sm and RNP is not clear; the present study was conducted to define these two different nuclear antigens. Rabbit thymus extracts were us...
The antibodies to ribonucleoprotein (RNP) and Sm antigen were studied in patients with various connective tissue diseases including systemic lupus erythematosus (SLE) (150), scleroderma (28), polymyositis (25), rheumatoid arthritis (25), mixed connective tissue diseases (MCTD) (29), sclerodermatomy...
Autoantibodies to small nuclear ribonucleoproteins (snRNPs) such as anti-Sm and U1RNP were among the first antinuclear protein responses identified in systemic autoimmune rheumatic diseases (SARD). Anti-Sm antibodies that recognize U1, U2, U5, and U4-6snRNPs are a marker for systemic lupus erythema...