www.nature.com/scientificreports OPEN Crystal structure and SUMO binding of Slx1-Slx4 complex received: 15 September 2015 accepted: 11 December 2015 Published: 20 January 2016 Fu-Ming Lian, Si Xie & Chengmin Qian The SLX1-SLX4 complex is a structure-specific endonuclease that cleaves ...
The SLX1-SLX4 complex is a structure-specific endonuclease that cleaves branched DNA structures and plays significant roles in DNA recombination and repair in eukaryotic cells. The heterodimeric interaction between SLX1 and SLX4 is essential for the endonuclease activity of SLX1. Here, we present ...
circle formation. Predicted to be located in nucleoplasm. Predicted to be part of Slx1-Slx4 complex. Used to study Fanconi-like syndrome. Orthologous to several human genes including SLX1A (SLX1 homolog A, structure-specific endonuclease subunit). [provided by Alliance of Genome Resources, Apr ...