this signal upon evaluation the Ca-Flux in a more heterogenous cohort of individuals, who poten- tially have an affected immune response due to diverse comorbidities such as (undiagnosed) autoimmune dis- ease, o
PLCγ2 is an enzyme with a critical regulatory role in various immune and inflammatory pathways. PLCγ2 is involved in downstream receptor signaling where, upon receptor stimulation, it hydrolyses PIP2 (phosphatidylinositol 4,5-bisphosphate) to generate IP3 (inositol 1,4,5-triphosphate) and DAG (...