必应词典为您提供sleeping-beauty-transposon的释义,网络释义: 转座子;睡美人转座子;
The Sleeping Beauty (SB) transposon shows efficient transposition and long-term transgene expression in human cells, and is currently under clinical development for gene therapy. SB transposition occurs into the human genome in a random manner, which carries a risk of potential genoto...
the Sleeping Beauty睡美人 1.Body Narration: An Analysis on the Aesthetic Significance of The Sleeping Beauty;身体的言说:《睡美人》的审美意义 3)Sleeping Beauty transposon"睡美人"转座子 1.Advances in studies ofSleeping Beauty transposon;“睡美人”转座子的研究进展 4)Where is the sleeping Beauty C...
The latest generation, Sleeping Beauty transposon-based hyperactive vector (SB100X), is able to address the basic problem of non-viral approaches 鈥 that is, low efficiency of stable gene transfer. The combination of transposon-based non-viral gene transfer with the latest improvements of non-...
The Sleeping Beauty (SB) transposon system is an efficient non-viral gene transfer tool in mammalian cells, but its broad use has been hampered by uncontrolled transposase gene activity from DNA vectors, posing a risk of genome instability, and by the in
Sleeping Beauty transposon Introduction Miyoshi myopathy, limb girdle muscular dystrophy 2B, and distal anterior compartment myopathy are autosomal recessive muscle disorders caused by mutations in the gene encoding dysferlin (DYSF).1,2,3 They are encompassed by the term dysferlinopathy and affect the ...
1) Sleeping Beauty transposon system SB转座元2) transposable element 转座元件 1. Advances of transposable element in genome of protozoa parasite; 原生动物基因组转座元件的研究进展 2. Plant transposable elements are classified into two major groups: class Ⅰelements or retrotransposons and class Ⅱ...
To identify genes important for colorectal cancer (CRC) development and metastasis, we established a new metastatic mouse organoid model using Sleeping Beauty (SB) transposon mutagenesis. Intestinal organoids derived from mice carrying actively mobilizing SB transposons, an activating KrasG12D, and an ...
Fernando, S., Fletcher, B.S.Sleeping BeautyTransposon-Mediated Nonviral Gene Therapy.BioDrugs20, 219–229 (2006). https://doi.org/10.2165/00063030-200620040-00003 Download citation Published16 August 2012 Issue DateJuly 2006 DOIhttps://doi.org/10.2165/00063030-200620040-00003 ...
睡美人转座子系统 The Sleeping Beauty transposon system 睡美人 (SB,Sleeping Beauty) 转座子系统就是这样一种系统,其设计用于在脊椎动物中进行基因转移。该系统由两部分组成:1) SB转座酶,催化转座所需的酶;和 2) 一个包含基因表达盒的转座子,可以在基因组内进行易位。睡美人转座酶得名于它是从鱼类中发现的...