had no effect on REM sleep compared with saline. Though these results suggestforebrain areas. Consistent with the hypothesis that M1receptor subtypes may be involved, systemic administration ofbiperidenand other
Besides its ramifications for the health of individuals, sleep has macro-level economic implications. A recent study estimated the annual economic cost of poor sleep to the Australian population at $45.2 billion, comprising direct healthcare costs, the cost of associated health conditions, reduced pro...
The trait-like differ- ential vulnerability to sleep loss has received support from an fMRI study attempting to reveal the neural basis for the interindividual differences (Chuah et al 2006). They used a go/no-go task to measure response inhibition after 24 h of sleep deprivation. The results...
Understanding human sleep requires appropriate animal models. Sleep has been extensively studied in rodents, although rodent sleep differs substantially from human sleep. Here we investigate sleep in tree shrews, small diurnal mammals phylogenetically cl
In a study of 172 patients undergoing general surgery, Hwang et al37 observed a higher rate of postoperative complications in patients with an ODI ≥ 5 vs that in those with an ODI < 5 events per hour (15.3% vs 2.7%; adjusted OR, 7.2). The rate of complications increased from 2.7% ...
Further, volitional polyphasic sleep as a sleep-scheduling strategy must be considered distinct from polyphasic sleep as a result of sleep disruption, such as that reported by some participants in this study. Importantly, many of our findings were for those working day shifts, a relatively ...
From birth, we spend a third of our lives asleep. After decades of research, we’re still not sure why.
This is an observational study, and as such, can’t establish cause. The researchers acknowledge that the study relied on self-reporting rather than objective measurement and reflected one point in time only. Glaucoma might itself influence sleep patterns, rather than ...
Sleep is an essential human function but its regulation is poorly understood. Using accelerometer data from 85,670 UK Biobank participants, we perform a genome-wide association study of 8 derived sleep traits representing sleep quality, quantity and timi
1-Hz vs. 0.25-Hz). This was a proof-of-concept study; therefore, the analysis did not correct for type I errors due to multiple comparisons for the BB conditions. On the other hand, to prevent type 1 errors arising from conducting statistical tests across multiple channels simultaneously, ...