We aimed to study whether ACB increases the future risk of dementia in older adults with SCD. METHODS: The retrospective cohort analysis was carried out on 1496 older adults. Out of those, 109 older patients with SCD followed up over 36 months were......
Nocturnal disturbances are a common symptom experienced by People Living with Dementia (PLWD), and these often present prior to diagnosis. Whilst sleep anomalies have been frequently reported, most studies have been conducted in lab environments, which a
“Wherever possible, we recommend that people with dementia avoid using Z-drugs if their sleep disturbance can be managed in other ways. Non-pharmacological alternatives should be considered, and when Z-drugs are prescribed, patients should receive care that reduces or prevents the occurrence o...
Pharmacologic treatments may be useful for symptomatic treatment of insomnia and nighttime behavioral disturbances in dementia patients, but there have been few controlled trials demonstrating their efficacy or long-term safety. Clonazepam is highly effective for treating the nighttime behaviors associated ...
The reduced spindle activity likely underpins the more disrupted sleep and may be associated with reduced daytime functioning and quality of life and may also be an early biomarker for an increased risk of developing dementia later in life in children with DS.Similar...
(CPAP) adherence decreases the odds of AD dementia and slowed cognitive decline [95,96,97]. Importantly, a systematic review reported that PAP treatment adherence only covers mostly the first half of the night, which could potentially leave much of REM sleep OSA untreated, since REM sleep ...
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Alzheimer’s disease (AD), a neurodegenerative disorder characterized by an impairment in global cognition and progressive memory loss, has been the main cause of dementia and is quickly becoming one of the most lethal, expensive, and burdening diseases in this century [1]. In 2018, AD Internat...
Quality of life in patients with cognitive impairment: validation of the Quality of Life-Alzheimer's Disease scale in Portugal. Quality of Life-Alzheimer's Disease (QOL-AD) is a widely used scale for the study of quality of life in patients with dementia. The aim of this study is th......
Poor sleep and delirium are common in older patients but recognition and management are challenging, particularly in the intensive care unit (ICU) setting.